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Browse our anti-Glucuronic Acid Epimerase (GLCE) Antibodies

Full name:: anti-Glucuronic Acid Epimerase Antibodies (GLCE)

On www.antibodies-online.com are 17 Glucuronic Acid Epimerase (GLCE) Antibodies from 8 different suppliers available. Additionally we are shipping Glucuronic Acid Epimerase Kits (10) and Glucuronic Acid Epimerase Proteins (7) and many more products for this protein. A total of 38 Glucuronic Acid Epimerase products are currently listed.

Synonyms:: 1110017N23Rik, AI747411, C130034A12Rik, glce, Hsepi, MGC79110, RGD1565253

list all antibodies	Gene Name	GeneID	UniProt
	GLCE	26035	O94923
	GLCE	363073
Anti-Mouse GLCE	GLCE	93683	Q9EPS3
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Most Popular Reactivities for anti-Glucuronic Acid Epimerase (GLCE) Antibodies

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Relevant Pathways for anti-Glucuronic Acid Epimerase Antibodies

Glycosaminoglycan Metabolic Process

More product categories related to Glucuronic Acid Epimerase Antibody

Top referenced anti-Glucuronic Acid Epimerase Antibodies

Human Polyclonal GLCE Primary Antibody for WB - ABIN525556 : Baik, Gasimli, Yang, Datta, Zhang, Glass, Esko, Linhardt, Sharfstein: Metabolic engineering of Chinese hamster ovary cells: towards a bioengineered heparin. in Metabolic engineering 2012 (PubMed)
Human Polyclonal GLCE Primary Antibody for IP - ABIN949168 : Datta, Yang, Linhardt, Sharfstein: Modulation of heparan sulfate biosynthesis by sodium butyrate in recombinant CHO cells. in Cytotechnology 2015 (PubMed)
Human Polyclonal GLCE Primary Antibody for ICC, IF - ABIN4314574 : Young, Moshood, Zhang, Sarbacher, Mueller, Halper: Does BMP2 play a role in the pathogenesis of equine degenerative suspensory ligament desmitis? in BMC research notes 2018 (PubMed)
Chemical Monoclonal GLCE Primary Antibody for RIA, ELISA - ABIN2473965 : Gallagher, Walker: Molecular distinctions between heparan sulphate and heparin. Analysis of sulphation patterns indicates that heparan sulphate and heparin are separate families of N-sulphated polysaccharides. in The Biochemical journal 1985 (PubMed)
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More Antibodies against Glucuronic Acid Epimerase Interaction Partners

Human Glucuronic Acid Epimerase (GLCE) interaction partners

Substrate binding mode and catalytic mechanism of human heparan sulfate d-glucuronyl C5 epimerase.
Results show that overexpression of Hsepi alone resulted in an unexpected increase in heparan sulfate (HS) chain length. A Hsepi point-mutant (Y168A), devoid of catalytic activity, failed to affect chain length. Moreover, the effect of Hsepi overexpression on HS chain length was abolished by simultaneous overexpression of 2OST.
The obtained data suggest an involvement of GLCE rs3865014 in breast cancer development. Heterozygous AG genotype might be a risk factor for breast cancer susceptibility in Siberian women and is associated with aggressive ER-negative and triple-negative cancer subtypes.
The GLCE gene polymorphism rs3865014 appears to have biological relevance in human pathophysiology.
C5-epimerase and 2-O-sulfotransferase in association generate extended domains of consecutive GlcNS-IdoA2S Sequence.
GLCE may be used as a potential model to study the functional role of intratumor cell heterogeneity in prostate cancer progression.
activation of angiogenesis as a main molecular mechanism of pro-oncogenic effect of GLCE in prostate cancer.
positive correlation between miRNA-218 and GLCE mRNA, and negative correlation between miRNA-218 and GLCE protein levels in breast tissues and primary tumors in vivo, supporting a direct involvement of miRNA-218 in posttranscriptional regulation of GLCE
Chondroitin-glucuronate C5-epimerase is a potential candidate for tumour antigen with immunogenicity and the peptides derived from this antigen could be useful in hepatocellular carcinoma immunotherapy.
A correlation was observed between D-glucuronyl C5-epimerase (GLCE), TCF4 and beta-catenin expression in breast cancer cells and primary tumors, suggesting an important role for TCF4/beta-catenin in regulating GLCE expression both in vitro and in vivo.
The biphasic mode of C(5)-epi offers a novel mechanism to regulate the biosynthesis of HS with the desired biological functions.
Loss of D-glucuronyl C-5 epimerase is associated with small-cell lung cancer.
SNPs in GLCE are associated with triglyceride and HDL-C levels in Turks, and mouse studies support a role for glce in lipid metabolism.
The regulation of GLCE expression by 2 cis-acting elements of the beta-catenin-TCF4 complex located in the enhancer region of the promoter are reported.
in 82-84% of human breast tumors there is either downregulation or loss of D-glucuronyl C5-epimerase mRNA expression and significant decrease of the protein content

Mouse (Murine) Glucuronic Acid Epimerase (GLCE) interaction partners

Results found that loss of Glce leads to a delayed onset of hypertrophic differentiation combined with an expanded region of proliferating chondrocytes indicating increased Ihh signaling.
analysis of the activity of heparan sulfate C5-epimerase and its mutants by using engineered 2-O-sulfotransferase
modification of heparan sulfate by glucuronyl C5-epimerase is required for controlling the activity of molecules that are instructive for early lymphoid tissue morphogenesis
NDST-1 and C5-epimerase have roles in heparan sulfate structure alterations in mouse tissue

Glucuronic Acid Epimerase (GLCE) Antigen Profile

Antigen Summary

Heparan sulfate (HS) is a negatively charged cell surface polysaccharide required for the biologic activities of circulating extracellular ligands. GLCE is responsible for epimerization of D-glucuronic acid (GlcA) to L-iduronic acid (IdoA) of HS, which endows the nascent polysaccharide chain with the ability to bind growth factors and cytokines (Ghiselli and Agrawal, 2005

Alternative names and synonyms associated with Glucuronic Acid Epimerase (GLCE)

glucuronic acid epimerase (GLCE) antibody
glucuronic acid epimerase (Glce) antibody
glucuronic acid epimerase L homeolog (glce.L) antibody
glucuronic acid epimerase (glce) antibody
glucuronyl C5-epimerase (Glce) antibody
glucuronic acid epimerase b (glceb) antibody

1110017N23Rik antibody
AI747411 antibody
C130034A12Rik antibody
glce antibody
Hsepi antibody
MGC79110 antibody
RGD1565253 antibody

Protein level used designations for GLCE

D-glucuronyl C5-epimerase , UDP-glucuronic acid epimerase , glucuronyl C5-epimerase , heparan sulfate C5-epimerase , heparan sulfate epimerase , heparin/heparan sulfate-glucuronic acid C5-epimerase , heparin/heparan sulfate:glucuronic acid C5-epimerase , heparosan-N-sulfate-glucuronate 5-epimerase , hsepi , glucuronic acid epimerase , D-glucuronyl C5-epimerase-like , d-glucuronyl C5-epimerase-like , heparan sulfate-glucuronic acid C5-epimerase , heparin sulfate C5-epimerase , D-glucuronyl C5 epimerase B , glucuronyl C5-epimerase b

GENE ID	SPECIES
26035	Homo sapiens
281195	Bos taurus
363073	Rattus norvegicus
415566	Gallus gallus
432242	Xenopus laevis
453542	Pan troglodytes
487622	Canis lupus familiaris
694999	Macaca mulatta
100019166	Monodelphis domestica
100052581	Equus caballus
100154444	Sus scrofa
100402503	Callithrix jacchus
100457760	Pongo abelii
100556549	Anolis carolinensis
100592444	Nomascus leucogenys
93683	Mus musculus
100007670	Danio rerio

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Show all anti-Glucuronic Acid Epimerase (GLCE) Antibodies with Pubmed References

Human Glucuronic Acid Epimerase (GLCE) interaction partners

Mouse (Murine) Glucuronic Acid Epimerase (GLCE) interaction partners

Antigen Summary

Alternative names and synonyms associated with Glucuronic Acid Epimerase (GLCE)

Protein level used designations for GLCE