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Full name:: anti-2'-5'-Oligoadenylate Synthetase 2, 69/71kDa Antibodies (OAS2)

On www.antibodies-online.com are 84 2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2) Antibodies from 15 different suppliers available. Additionally we are shipping OAS2 Kits (9) and OAS2 Proteins (4) and many more products for this protein. A total of 106 OAS2 products are currently listed.

Synonyms:: Oasl11

list all antibodies	Gene Name	GeneID	UniProt
	OAS2	4939	P29728
	OAS2	246728
	OAS2	363938
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Relevant Pathways for anti-OAS2 Antibodies

Hepatitis C

More product categories related to OAS2 Antibody

More Antibodies against OAS2 Interaction Partners

Human 2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2) interaction partners

we characterized the functional consequences of the Neandertal haplotype in the transcriptional regulation of OAS (show SMOC1 Antibodies) genes at baseline and infected conditions. We found that cells from people with the Neandertal-like haplotype express lower levels of OAS3 (show OAS3 Antibodies) upon infection, as well as distinct isoforms of OAS1 (show OAS1 Antibodies) and OAS2
Suggest 2'5'-oligoadenylate synthetase 2 mediates T-cell receptor CD3-zeta (show CD247 Antibodies) chain down-regulation via caspase-3 (show CASP3 Antibodies) activation in oral cancer.
Data obtained suggest that the OAS2 rs1293762 and CD209 (show CD209 Antibodies) rs2287886 SNPs are associated with predisposition to chronic hepatitis C in Russian population.
Primary mononuclear cells from patients with systemic sclerosis have increased basal levels of OASL (show OASL Antibodies) and OAS2 genes.
The results suggest that OAS1 (show OAS1 Antibodies)-OAS3 (show OAS3 Antibodies)-OAS2 haplotypes are associated with differential susceptibility to clinical outcomes of dengue infection.
The data suggest a possible association between OAS2 and OAS3 (show OAS3 Antibodies) single nucleotide polymorphisms and the outcome of tick-borne encephalitis virus infection in a Russian population.
2'-5'-oligoadenylate synthetase type 2 (OAS2), a dsRNA binding protein involved in the pathway that activates RNase-L (show RNASEL Antibodies), is identified as a new binding partner for NOD2 (show NOD2 Antibodies).

Mouse (Murine) 2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2) interaction partners

A non-synonymous mutation in Oas2 (I405N) in the viral sensor Oas2 was found and the mutation caused post-partum failure of lactation in healthy mice with otherwise normally developed mammary glands, characterized by greatly reduced milk protein synthesis coupled with epithelial cell death, inhibition of proliferation and a robust interferon (show IFNA Antibodies) response. The mutation activates the OAS2 pathway.

OAS2 Antigen Profile

Antigen Summary

This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.

Alternative names and synonyms associated with OAS2

2'-5'-oligoadenylate synthetase 2 (OAS2) antibody
2'-5' oligoadenylate synthetase 2 (Oas2) antibody
2'-5'-oligoadenylate synthetase 2, 69/71kDa (OAS2) antibody

Oasl11 antibody

Protein level used designations for OAS2

(2'-5')oligo(A) synthetase 2 , 2'-5'-oligoadenylate synthase 2 , 2-5A synthase 2 , p69 OAS / p71 OAS , (2-5')oligo(A) synthase 2 , 2',5'-oligoadenylate synthetase-like 11 , 2'-5' oligoadenylate synthetase-like 11 , 2,5-oligoadenylate synthetase-like 11 , 2'-5'-oligoadenylate synthetase 2, 69/71kDa , 2'-5' oligoadenylate synthetase 2 , 2',5'-oligoadenylate synthetase 2 , 2'-5'-oligoadenylate synthetase 2-like , 2'-5'-oligoadenylate synthase 2-like

GENE ID	SPECIES
4939	Homo sapiens
246728	Mus musculus
363938	Rattus norvegicus
529660	Bos taurus
595128	Sus scrofa
611051	Canis lupus familiaris
739230	Pan troglodytes
791250	Equus caballus
100385728	Callithrix jacchus
100444286	Pongo abelii
100468112	Ailuropoda melanoleuca
100588209	Nomascus leucogenys
100340787	Oryctolagus cuniculus

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