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anti-Human GATA3 Antibodies:
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Human Monoclonal GATA3 Primary Antibody for ELISA, WB - ABIN969167
Mehra, Varambally, Ding, Shen, Sabel, Ghosh, Chinnaiyan, Kleer: Identification of GATA3 as a breast cancer prognostic marker by global gene expression meta-analysis. in Cancer research 2005
Show all 6 Pubmed References
Human Monoclonal GATA3 Primary Antibody for WB - ABIN1944795
Joulin, Bories, Eléouet, Labastie, Chrétien, Mattéi, Roméo: A T-cell specific TCR delta DNA binding protein is a member of the human GATA family. in The EMBO journal 1991
Show all 5 Pubmed References
Human Monoclonal GATA3 Primary Antibody for IHC, ELISA - ABIN969168
Muzzioli, Stecconi, Moresi, Provinciali: Zinc improves the development of human CD34+ cell progenitors towards NK cells and increases the expression of GATA-3 transcription factor in young and old ages. in Biogerontology 2009
Show all 2 Pubmed References
Human Polyclonal GATA3 Primary Antibody for ELISA, IHC - ABIN4313648
Marine, Winoto: The human enhancer-binding protein Gata3 binds to several T-cell receptor regulatory elements. in Proceedings of the National Academy of Sciences of the United States of America 1991
Cow (Bovine) Polyclonal GATA3 Primary Antibody for IF, IHC - ABIN2779713
Kaminuma, Kitamura, Kitamura, Miyagishi, Taira, Yamamoto, Miura, Miyatake: GATA-3 suppresses IFN-gamma promoter activity independently of binding to cis-regulatory elements. in FEBS letters 2004
Show all 2 Pubmed References
Human Monoclonal GATA3 Primary Antibody for ELISA, ICC - ABIN4313647
Ono, Yu, Kasahara, Kikuchi, Ishii, Tomita: Fluorescently activated cell sorting followed by microarray profiling of helper T cell subtypes from human peripheral blood. in PLoS ONE 2014
GATA3 mutations, recently observed in breast cancer, encode active transcription factors.
KMT1A (show SUV39H1 Antibodies) positively regulated the self-renewal and tumorigenicity of human Bladder cancer stem cells via KMT1A (show SUV39H1 Antibodies)-GATA3-STAT3 (show STAT3 Antibodies) circuit, in which KMT1A (show SUV39H1 Antibodies) could be a promising target for bladder cancer therapy.
Defective sirtuin-1 (show SIRT1 Antibodies) was found to increase IL-4 (show IL4 Antibodies) expression through acetylation of GATA-3 in patients with severe asthma compared with healthy controls.
GATA3 activation was diminished upon cultivation of T cells with RNase 7 (show RNASE7 Antibodies).
overexpression of GATA3 and FOXA1 (show FOXA1 Antibodies) cooperate with PPAR (show PPARA Antibodies) activation to drive transdifferentiation of a basal bladder cancer cells to a luminial phenotype.
The data have demonstrated that GATA3 is by far the most reliable breast-specific immunomarker in both surgical and cytological specimens
GATA3 interacts with and is acetylated by the acetyltransferase CBP (show CREBBP Antibodies). The major acetylated site of GATA3 in lung adenocarcinoma cells is lysine 119.
GATA3 may be useful as a part of a panel of immunohistochemical markers in narrowing the differential diagnosis between pheochromocytoma and adrenal cortical carcinoma
Authors demonstrated that ER(alpha (show ESR1 Antibodies)), GATA3 and FOXA1 (show FOXA1 Antibodies) form a transcriptional complex with Ell3 (show ELL3 Antibodies) to regulate IL-20 (show IL20 Antibodies) expression in ER(+) breast cancer cells. FOXA1 (show FOXA1 Antibodies) represses IL-20 (show IL20 Antibodies) expression, whereas GATA3 and ER(alpha (show ESR1 Antibodies)) activate it.
We have identified ZPO2 as a negative regulator of GATA3, thus providing an alternative mechanism that results in a reduction in or perhaps even loss of GATA3 during breast cancer development.
Transcription factor GATA3 is responsible for the ER stress-induced TRIP-Br2 (show SERTAD2 Antibodies) expression in visceral fat.
GATA-3 participates in the healing of bone fractures via regulating bcl-xL (show BCL2L1 Antibodies) gene expression, owing to its association with Runx2 (show RUNX2 Antibodies).
Gata3 deficiency promotes B cell differentiation and proliferation, and cooperates with p18 (show CDKN2C Antibodies) loss to induce B cell lymphomas
Findings suggest that VEGF (show VEGFA Antibodies) gene expression can be suppressed by TNFSF15 (show TNFSF15 Antibodies)-stimulated activation of the JNK (show MAPK8 Antibodies)-GATA3 signaling pathway which gives rise to up-regulation of miR (show MLXIP Antibodies)-29b.
RHS6 is a critical regulatory element for allergic airway inflammation and for coordinate regulation of Th2 cytokine genes by recruiting GATA3, SATB1 (show SATB1 Antibodies), and IRF4 (show IRF4 Antibodies).
the model of mutually antagonistic differentiation programs driven by mutually exclusively expressed T-bet or GATA-3 does not completely explain natural CD4 (show CD4 Antibodies) T cell priming outcomes
MIF (show MIF Antibodies)-deficient mice have reduced Nippostrongylus brasiliensis burden and mounted an enhanced type 2 immune response, including increased Gata3 expression and IL-13 (show IL13 Antibodies) production in the mesenteric lymph nodes
study demonstrates a role for HOX5 (show HOXB5 Antibodies) proteins in controlling lung inflammation during a model of allergic asthma. The increased inflammation in the Hox5 (show HOXB5 Antibodies)-deficient mice was mediated by increased Th2 cell development, which was associated with regulation of Gata3 expression
Treg cell accumulation in intestinal tumours from APC (show APC Antibodies)(min/+) mice was exclusively due to the increase in KLRG1 (show KLRG1 Antibodies)(+) GATA3(+) Treg cells.
gata3 acts as a specific injury-induced proregenerative factor that is essential for the regenerative capacity in vertebrates
GATA2 (show GATA2 Antibodies) and/or GATA3 are involved in the regulation of trophoblast-specific gene transcription in bovine trophoblast CT-1 (show SLC6A8 Antibodies) cells
study identified rainbow trout and Atlantic salmon IL-4 (show IL4 Antibodies)/13A, a homologue of mammalian Th2 cytokine genes IL-4 (show IL4 Antibodies) and IL-13 (show IL13 Antibodies); salmonid IL-4 (show IL4 Antibodies)/13A and GATA-3 were found highly expressed in thymus, gill, and skin
T cells expressed low levels of GATA-3, which decreased with age.
The myocardial immune dysfunction induced by the change in expression levels of the transcription factors GATA-3 and T-bet may be involved in the process of post-resuscitation myocardial injury in a porcine model of cardiac arrest.
Pig GATA-3 cDNA was obtained by reverse transcription polymerase chain reaction (RT-PCR), using in silico cloning strategy based on pig dbEST (show BEST1 Antibodies).
This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia.
GATA-binding factor 3
, trans-acting T-cell-specific transcription factor GATA-3
, GATA-binding protein 3
, transcription factor GATA-3
, GATA binding factor-3
, transcription factor xGATA-3
, transcription factor NF-E1c
, GATA binding protein 3
, putative amidase
, trans-acting T-cell-specific transcription factor GATA-3-like