We are preparing the requested document. Please wait, this may take a while...!
There was a problem generating the requested document, please try again.
GRF2 Antigen Profile
This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.
Alternative names and synonyms associated with GRF2