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CoCoA and CCAR1 appear to relay the GATA1 (show GATA1 Proteins) signal to MED1 (show MBD4 Proteins), and multiple modes of the GATA1 (show GATA1 Proteins)-MED1 (show MBD4 Proteins) axis may help to fine-tune GATA1 (show GATA1 Proteins) function during GATA1 (show GATA1 Proteins)-mediated homeostasis events.
Results report a novel human protein, calphoglin, which activates inorganic pyrophosphatase (IPP) and enhances phosphoglucomutase activity through the activated IPP.
CoCoA uses different combinations of functional domains in its synergistic coactivator function with beta-catenin (show CTNNB1 Proteins) or GRIP1 (show NCOA2 Proteins)
The N terminus of CoCoA contains another activation domain , which is necessary and sufficient for synergistic activation of LEF1 (show LEF1 Proteins)-mediated transcription by CoCoA and beta-catenin (show CTNNB1 Proteins).
May function as a coactivator for aryl hydrocarbon and nuclear receptors (By similarity).
calcium binding and coiled-coil domain 1
, coiled-coil transcriptional coactivator
, calcium-binding and coiled-coil domain-containing protein 1-like
, calcium-binding and coiled-coil domain-containing protein 1
, GRIP1-interacting protein
, coiled-coil coactivator protein
, granule cell antiserum positive 11
, coiled-coil leucine zipper coactivator 1
, inorganic pyrophosphatase activator
, sarcoma antigen NY-SAR-3