Protein Summary

The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.

Alternative names and synonyms associated with Angiotensin II (Ang II)

• angiotensinogen (AGT) antibody
• angiotensinogen (Agt) antibody
• angiotensinogen (serpin peptidase inhibitor, clade A, member 8) (Agt) antibody

• AI265500 antibody
• Ang antibody
• AngI antibody
• AngII antibody
• ANHU antibody
• Show all synonym aliases
• ANRT antibody
• Aogen antibody
• PAT antibody
• Serpina8 antibody

Protein level used designations for Angiotensin II (Ang II) ELISA Kits

alpha-1 antiproteinase, antitrypsin , angiotensin I , angiotensin II , angiotensinogen , pre-angiotensinogen , serine (or cysteine) proteinase inhibitor , serpin A8 , angiotensinogen (PAT) , angiotensin ll