Browse our anti-SRC (SRC) Antibodies

Full name:: anti-V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) Antibodies (SRC)

On www.antibodies-online.com are 477 V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) Antibodies from 31 different suppliers available. Additionally we are shipping SRC Proteins (21) and SRC Kits (16) and many more products for this protein. A total of 540 SRC products are currently listed.

Synonyms:: ASV, AW259666, c-Src, C-src1, CG7524, D-src, D-Src64B, Dmel\CG7524, DmHD-358, Dm SRC1, dsrc, Dsrc64, Dsrc64B, HD-358, MRE5, p60-Src, PP60C-SCR, pp60c-src, SDR, src, SRC1, src64, SRC 64B, src64b

list all antibodies	Gene Name	GeneID	UniProt
	SRC	20779	P05480
	SRC	6714	P12931
	SRC	83805
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Most Popular Reactivities for anti-SRC (SRC) Antibodies

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anti-Mouse (Murine) SRC Antibodies:

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anti-Rat (Rattus) SRC Antibodies:

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Top referenced anti-SRC Antibodies

Human Polyclonal SRC Primary Antibody for IHC - ABIN967081 : David-Dufilho, Millanvoye-Van Brussel, Topal, Walch, Brunet, Rendu: Endothelial thrombomodulin induces Ca2+ signals and nitric oxide synthesis through epidermal growth factor receptor kinase and calmodulin kinase II. in The Journal of biological chemistry 2005 (PubMed)
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Human Polyclonal SRC Primary Antibody for FACS, IF - ABIN1881833 : Kieslinger, Hiechinger, Dobreva, Consalez, Grosschedl: Early B cell factor 2 regulates hematopoietic stem cell homeostasis in a cell-nonautonomous manner. in Cell stem cell 2010 (PubMed)
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Human Polyclonal SRC Primary Antibody for WB - ABIN1881832 : Pradhan, Alrehani, Patel, Khatlani, Vijayan: Cross-talk between serine/threonine protein phosphatase 2A and protein tyrosine phosphatase 1B regulates Src activation and adhesion of integrin αIIbβ3 to fibrinogen. in The Journal of biological chemistry 2010 (PubMed)
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Human SRC Primary Antibody for IHC - ABIN967080 : Parker, Mardon, Lebo, Varmus, Bishop: Isolation of duplicated human c-src genes located on chromosomes 1 and 20. in Molecular and cellular biology 1985 (PubMed)
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Human Polyclonal SRC Primary Antibody for IHC - ABIN967082 : Pyper, Bolen: Identification of a novel neuronal C-SRC exon expressed in human brain. in Molecular and cellular biology 1990 (PubMed)
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Human Monoclonal SRC Primary Antibody for ELISA, WB - ABIN1724696 : Li, Aurandt, Jürgensen, Jürgense, Rao, Guan: FAK and Src kinases are required for netrin-induced tyrosine phosphorylation of UNC5. in Journal of cell science 2005 (PubMed)
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Chicken Monoclonal SRC Primary Antibody for ICS - ABIN1177179 : Alvarez, Kantarjian, Cortes: The role of Src in solid and hematologic malignancies: development of new-generation Src inhibitors. in Cancer 2006 (PubMed)
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Chicken Monoclonal SRC Primary Antibody for ICS - ABIN1177181 : Arias-Salgado, Lizano, Sarkar, Brugge, Ginsberg, Shattil: Src kinase activation by direct interaction with the integrin beta cytoplasmic domain. in Proceedings of the National Academy of Sciences of the United States of America 2003 (PubMed)
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Chicken Monoclonal SRC Primary Antibody for ICS - ABIN1177180 : Frame: Newest findings on the oldest oncogene; how activated src does it. in Journal of cell science 2004 (PubMed)
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Human Monoclonal SRC Primary Antibody for IF, WB - ABIN387822 : Chen, Li, Zhang, Yi, Chen, Wang, Zhang: Src-stimulated IRTKS phosphorylation enhances cell migration. in FEBS letters 2011 (PubMed)
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More Antibodies against SRC Interaction Partners

Mouse (Murine) V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) interaction partners

Src kinase (show CSK Antibodies) activation by nitric oxide promotes resistance to anoikis in tumor cell lines.
RANKL (show TNFSF11 Antibodies) and Src has an unrecognized role in osteocyte survival.
These interactions are required for SRC-induced activation of VAV (show VAV1 Antibodies) and the subsequent engagement of a JIP1 (show MAPK8IP1 Antibodies)-tethered JNK (show MAPK8 Antibodies) signaling module.
Elevated retinoic acid-inducible gene 1 (show RARRES3 Antibodies) (RIG-I (show DDX58 Antibodies)) modulated the interaction of activated proto-oncogene c-Src (Src) and STAT3 (show STAT3 Antibodies) by competitive binding to STAT3 (show STAT3 Antibodies).
Cbl, Cbl-b, and Cbl-c have a role in protecting mammary epithelial cellsfrom proteotoxic stress-induced cell death by promoting turnover of active c-Src
unlike c-fos-/- mice, c-src-/- mice demonstrated activated, mature osteoblasts, and parallel layers of cement lines in the superficial bone matrix, indicating the new bones were piled up to older bone.
TM, especially TME45, maintains vascular integrity, at least in part, via Src signaling.
We conclude that pp60(Src) can directly inhibit DDAH (show DDAH2 Antibodies) II and this is involved in the increased ADMA levels that enhance eNOS (show NOS3 Antibodies) uncoupling during the development of acute lung injury (ALI).
Ambra1 (show AMBRA1 Antibodies) binds to both FAK (show PTK2 Antibodies) and Src in cancer cells. When FAK (show PTK2 Antibodies) is present, Ambra1 (show AMBRA1 Antibodies) is recruited to focal adhesions, promoting FAK (show PTK2 Antibodies)-regulated cancer cell direction-sensing and invasion. However, when Ambra1 (show AMBRA1 Antibodies) cannot bind to FAK (show PTK2 Antibodies), abnormally high levels of phospho-Src and phospho-FAK (show PTK2 Antibodies) accumulate at focal adhesions, positively regulating adhesion and invasive migration.
Thus we propose that Cx43 (show GJA1 Antibodies) might enhance the activation of Nrf2 (show NFE2L2 Antibodies)/ARE pathway by means of inhibiting c-Src activity to hinder the nuclear export of Nrf2 (show NFE2L2 Antibodies), and then reduce expression of FN, ICAM-1 (show ICAM1 Antibodies) and TGF-b1, ultimately attenuating renal fibrosis in diabetes.

Fruit Fly (Drosophila melanogaster) V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) interaction partners

Src overexpression alone activated the Jun N-terminal Kinase (JNK (show MAPK8 Antibodies)) signalling pathway to promote actin (show ACTB Antibodies) cytoskeletal and cell polarity defects and drive apoptosis in in a whole epithelial tissue context in the Drosophila eye, whereas, in cooperation with RasACT, JNK (show MAPK8 Antibodies) led to a loss of differentiation and an invasive phenotype.
Src64 controls actin dynamics to mediate proper ring canal formation during incomplete cytokinesis during germline cyst development in vivo
that Brat represses the translation of src64B, an upstream regulator of a conserved Rho-dependent pathway previously shown to promote axon retraction
Results show that Src42a and Src64b are required for the normal division capacity of Drosophila intestinal progenitor cells, and that these genes as well as Ack cause progenitor overproliferation in the intestine via core cell cycle activation.
a novel essential role for Src in intestinal stem/progenitor cell proliferation and tumourigenesis initiation in vivo.
Data show that the actin-Capping Protein (show TMOD4 Antibodies) (CP) alphabeta heterodimer, which regulates actin (show ACTB Antibodies) filament (F-actin (show ACTB Antibodies)) polymerization, limits Src-induced apoptosis or tissue overgrowth by restricting JNK (show MAPK8 Antibodies) activation.
Dumbfounded/Neph1 (show NEPH1 Antibodies), a key diaphragm constituent, is a target of the Src kinase (show CSK Antibodies) Src64B. Loss of Src64B activity leads to a reduction in the number of diaphragms, and this effect is in part mediated by loss of Dumbfounded/Neph1 (show NEPH1 Antibodies) tyrosine phosphorylation.
Homodimerization of the Wnt receptor DERAILED recruits the Src family kinase SRC64B in the developing embryonic central nervous system.
E4orf4 has a role in inducing PP2A (show PPP2R2B Antibodies)- and Src-dependent cell death while inhibiting classic apoptosis pathways in Drosophila melanogaster
Mutations in a Drosophila src gene, src64, that alter the three HRD amino acids, were identified.

Human V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) interaction partners

Src kinase (show CSK Antibodies) activation by nitric oxide promotes resistance to anoikis in tumor cell lines.
Src and Aurora-A (show AURKA Antibodies) interact upon Golgi ribbon fragmentation; Src phosphorylates Aurora-A (show AURKA Antibodies) at tyrosine 148 and this specific phosphorylation is required for Aurora-A (show AURKA Antibodies) localization at the centrosomes.
Study demonstrated that c-Src contributed to hypoxic microenvironment-rendered paclitaxel resistance in human epithelial ovarian cancer cells by G2/M phase arrest deterioration, and through c-Src suppression, FV-429 was capable of reversing the resistance by blocking c-Src/Stat3 (show STAT3 Antibodies)/HIF-1alpha (show HIF1A Antibodies) pathway.
Data demonstrated that the Src/Fn14 (show TNFRSF12A Antibodies)/NF-kappaB (show NFKB1 Antibodies) axis plays a critical role in NSCLC metastasis.
Results suggest that Src promotes EGF (show EGF Antibodies)-stimulated EMT (show ITK Antibodies) and migration by upregulation of ZEB1 (show ZEB1 Antibodies) and ZEB2 (show ZEB2 Antibodies) through AKT (show AKT1 Antibodies) signaling pathway in gastric cancer cells.
Combined targeting of AKT (show AKT1 Antibodies) and SRC resulted in a synergistic efficacy against human pancreatic cancer growth and metastasis.
important roles for c-Src tyrosine kinase (show CSK Antibodies) in phosphorylation and activation of SLC11A1 (show SLC11A1 Antibodies) in macrophages
Our data suggest that targeting Src signaling may be an effective approach to the treatment of ALK-non-small cell lung cancer (NSCLC) with acquired resistance to ALK inhibitors.
Src kinase (show CSK Antibodies) in chemo-naive human primary osteosarcoma cells is differentially activated.
This study demonstrates that simultaneous inhibition of c-Met and Src signaling in MD-MSCs triggers apoptosis and reveals vulnerable pathways that could be exploited to develop NF2 (show NF2 Antibodies) therapies.

Cow (Bovine) V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) interaction partners

RhoA (show RHOA Antibodies) and membrane fluidity mediates the spatially polarized Src/FAK (show PTK2 Antibodies) activation in response to shear stress.
AngII activates PKD via a mechanism involving Src family kinases and PKC, to underlie increased aldosterone production.
The Src gene possibly contributed to conducting association analysis and can be recognized as genetic marker in milk production traits and other performance for animal breeding and genetics.
src has a role in activation of 5'-AMP (show TMPRSS5 Antibodies)-activated kinase during hypoxia-reoxygenation of bovine aortic endothelial cells
results indicate that integrin engagement disrupts VE-cadherin-containing adherens junctions via the activation of Src, but not Ras, possibly as a result of modulation of the actin network
These results suggest that TGF-beta1 (show TGFB1 Antibodies)-induced monolayer permeability involves focal adhesion and cytoskeletal rearrangement through both FAK (show PTK2 Antibodies)/Src-dependent and -independent pathways.

Pig (Porcine) V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) interaction partners

The findings are consistent with previous studies that indicate a link between Na,K-ATPase (show ATP1A1 Antibodies) activity and SFK signaling.
Src kinase (show CSK Antibodies) mediates hypoxia-induced caspase-1 (show CASP1 Antibodies) activation in the cerebral cortex of newborn piglets
Expression of mutant alpha1 Na/K-ATPase (show ATP1A1 Antibodies) defective in conformational transition attenuates Src-mediated signal transduction
20-HETE activates the Raf/MEK/ERK pathway in renal epithelial cells through an EGFR- and c-Src-dependent mechanism.

SRC Antigen Profile

Antigen Summary

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.

Alternative names and synonyms associated with SRC

SRC proto-oncogene, non-receptor tyrosine kinase (SRC) antibody
uncharacterized LOC5574802 (LOC5574802) antibody
proto-oncogene tyrosine-protein kinase src (CpipJ_CPIJ010659) antibody
Rous sarcoma oncogene (Src) antibody
Src oncogene at 64B (Src64B) antibody
SRC proto-oncogene, non-receptor tyrosine kinase (Src) antibody

ASV antibody
AW259666 antibody
c-Src antibody
C-src1 antibody
CG7524 antibody
D-src antibody
D-Src64B antibody
Dmel\CG7524 antibody
DmHD-358 antibody
Dm SRC1 antibody
dsrc antibody
Dsrc64 antibody
Dsrc64B antibody
HD-358 antibody
MRE5 antibody
p60-Src antibody
PP60C-SCR antibody
pp60c-src antibody
SDR antibody
src antibody
SRC1 antibody
src64 antibody
SRC 64B antibody
src64b antibody

Protein level used designations for SRC

, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , proto-oncogene tyrosine-protein kinase SRC proto-oncogene tyrosine-protein kinase src neuronal proto-oncogene tyrosine-protein kinase Src p60-Src proto-oncogene c-Src CG7524-PB CG7524-PC CG7524-PD CG7524-PE CG7524-PF CG7524-PG CG7524-PH CG7524-PI CG7524-PJ Src proto oncogene sequence Src64B-PB Src64B-PC Src64B-PD Src64B-PE Src64B-PF Src64B-PG Src64B-PH Src64B-PI Src64B-PJ mRNA-like ncRNA in embryogenesis 5 proto-oncogene tyrosine-protein kinase Src protooncogene SRC, Rous sarcoma tyrosine kinase pp60c-src tyrosine-protein kinase SRC-1 Rous sarcoma oncogene c-Src pp60c-src tyrosine protein kinase c-src tyrosine protein kinase pp60-c-src v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog src oncogene v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog non-tyrosine protein kinase

GENE ID	SPECIES
458229	Pan troglodytes
5574802	Aedes aegypti
6043642	Culex quinquefasciatus
20779	Mus musculus
48973	Drosophila melanogaster
6714	Homo sapiens
83805	Rattus norvegicus
485864	Canis lupus familiaris
535742	Bos taurus
100154503	Sus scrofa
396442	Gallus gallus

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Show all anti-V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) Antibodies with Pubmed References