Browse our STAT1 Proteins (STAT1)

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.

• signal transducer and activator of transcription 1 (STAT1)
• signal transducer and activator of transcription 1 (Stat1)
• signal transducer and activator of transcription 1 L homeolog (stat1.L)
• signal transducer and activator of transcription 1, 91kDa (STAT1)
• signal transducer and activator of transcription 4 (stat4)

• 2010005J02Rik protein
• AA408197 protein
• CANDF7 protein
• DD6G4-4 protein
• dZ182H3.3 protein
• Show all synonym aliases
• ISGF-3 protein
• si:by51f19.1 protein
• si:by134g18.2 protein
• si:dz73o4.2 protein
• si:dz182h3.3 protein
• si:dz199m19.1 protein
• STAT protein
• STAT1 protein
• STAT4 protein
• STAT91 protein
• XStat1 protein

signal transducer and activator of transcription 1-alpha/beta , signal transducer and activator of transcription-1 , transcription factor ISGF-3 components p91/p84 , signal transducer and activator of transcription 1 , signal transducer and activator of transcription 4 , transcription factor ISGF-3 , activator of transcription , signal transduction , LOW QUALITY PROTEIN: signal transducer and activator of transcription 1-alpha/beta , signal transducer and activator of transcription 1, 91kDa