Synonyms: ANGIE, ANGIE2, B cell attracting chemokine 1, B cell chemoattractant, B cell homing chemokine (ligand for Burkitt's lymphoma receptor 1), B lymphocyte chemoattractant, BCA 1, BLC, BLR1L, C X C motif chemokine 13, Chemokine (C X C motif) ligand 13, Chemokine CXC motif ligand 13, CXC chemokine BLC, CXCL13, SCYB13, Small inducible cytokine B subfamily (Cys X Cys motif) member 13 (B cell chemoattractant), Small inducible cytokine B13, Small inducible cytokine subfamily B member 13
Background: C-X-C motif chemokine 13(CXCL13), also known as B lymphocyte chemoattractant(BLC), is a protein that in humans is encoded by theCXCL13 gene. CXCL13 is a small cytokine belonging to the CXC chemokine family, and it was located on sequence maps to 4q21, near the genes encoding most CXC chemokines. In T-lymphocytes, CXCL13 expression is thought to reflect a germinal center origin of the T-cell. Hence, expression of CXCL13 in T-cell lymphomas, such as Angioimmunoblastic T-cell Lymphoma, is thought to reflect a germinal center origin of the neoplastic T-cells.
Gene Name: CXCL13
Production: Natural and recombinant mouse CXCL13. There is no detectable cross-reactivity with other relevant proteins.
Standard: Expression system for standard: E.coli, Immunogen sequence: I22-A109