Protein Summary

This gene encodes a member of the p34Cdc2 protein kinase family. p34Cdc2 kinase family members are known to be essential for eukaryotic cell cycle control. This gene is in close proximity to CDC2L1, a nearly identical gene in the same chromosomal region. The gene loci including this gene, CDC2L1, as well as metalloprotease MMP21\\/22, consist of two identical, tandemly linked genomic regions, which are thought to be a part of the larger region that has been duplicated. This gene and CDC2L1 were shown to be deleted or altered frequently in neuroblastoma with amplified MYCN genes. The protein kinase encoded by this gene could be cleaved by caspases and was demonstrated to play roles in cell apoptosis. Many transcript variants encoding several different isoforms have been found for this gene, but the full-length nature of only two have been determined so far.

Alternative names and synonyms associated with Cyclin-Dependent Kinase 11A (CDK11A)

• cyclin dependent kinase 11A (CDK11A) antibody
• cyclin-dependent kinase 11A (LOC100338292) antibody

• CDC2L1 antibody
• CDC2L2 antibody
• CDC2L3 antibody
• CDK11-p46 antibody
• CDK11-p58 antibody
• Show all synonym aliases
• CDK11-p110 antibody
• cPITSLRE antibody
• p58GTA antibody
• PITSLRE antibody

Protein level used designations for CDK11A

PITSLRE B , PITSLRE protein kinase beta , PITSLRE serine/threonine-protein kinase CDC2L2 , cell division cycle 2-like 2 (PITSLRE proteins) , cell division cycle 2-like protein kinase 2 , cell division protein kinase 11A , galactosyltransferase-associated protein kinase p58/GTA , cyclin-dependent kinase 11A , cyclin-dependent kinase 11B , cell division cycle 2-like 1 (PITSLRE proteins) , cell division protein kinase 11 , protein kinase