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anti-Human G3BP2 Antibodies:
anti-Mouse (Murine) G3BP2 Antibodies:
anti-Rat (Rattus) G3BP2 Antibodies:
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Human Polyclonal G3BP2 Primary Antibody for ICC, IF - ABIN4313043
Wei, Fattet, Tsai, Guo, Pai, Majeski, Chen, Sah, Taylor, Engler, Yang: Matrix stiffness drives epithelial-mesenchymal transition and tumour metastasis through a TWIST1-G3BP2 mechanotransduction pathway. in Nature cell biology 2015
Show all 2 Pubmed References
Human Polyclonal G3BP2 Primary Antibody for ICC, IF - ABIN4313044
Katz, Sims, Sproul, Caldwell, Dixon, Meehan, Harrison: Targeting of Rac GTPases blocks the spread of intact human breast cancer. in Oncotarget 2012
Show all 2 Pubmed References
High G3BP2 levels worsened prognosis in breast cancer. Cell lines with lower G3BP2 levels required substantially higher cell numbers to form tumors in NOD/SCID (show PRKDC Antibodies) mice. G3BP2 regulates SART3 (show SART3 Antibodies), Nanog (show NANOG Antibodies), and Oct-4 (show POU5F1 Antibodies) expression levels and may be responsible for the maintenance of subpopulations of breast cancer cells with long-term proliferative properties.G3BP2 is important in breast tumor initiation.
Translocation of p53 (show TP53 Antibodies) is regulated by androgen-dependent sumoylation mediated by the G3BP2-interacting SUMO-E3 ligase (show PIAS1 Antibodies), RanBP2 (show RANBP2 Antibodies). G3BP2 knockdown results in reduced tumor growth and increased nuclear p53 (show TP53 Antibodies) accumulation in mouse xenograft models of prostate cancer with or without long-term androgen deprivation.
G3BP (show G3BP1 Antibodies) mediates the condensation of stress granules by shifting between two different states that are controlled by the phosphorylation of S149 and by binding to Caprin1 or USP10 (show USP10 Antibodies).
FGDF peptide binds and changes conformation of the protruding N-terminal residues by providing hydrophobic interactions to a symmetry related molecule that facilitated crystallization of the G3BP2 isoform.
G3BP1, G3BP2 and CAPRIN1 are required for translation of interferon stimulated mRNAs and are targeted by a dengue virus non-coding RNA.
Reveal a TWIST1 (show TWIST1 Antibodies)-G3BP2 mechanotransduction pathway that responds to biomechanical signals from the tumour microenvironment to drive EMT (show ITK Antibodies), invasion and metastasis.
Stress granule components G3BP1 (show G3BP1 Antibodies) and G3BP2 play a proviral role early in Chikungunya virus replication.
both G3BP1 (show G3BP1 Antibodies) and G3BP2 play a role in the formation of SGs (show FBN1 Antibodies) in various human cells and thereby recovery from these cellular stresses.
Data show that the nsP3 (show SH2D3C Antibodies)/G3BP (show G3BP1 Antibodies) interaction also blocks stress granules (SGs (show FBN1 Antibodies)) induced by other stresses than virus infection.
first evidence of direct interactions between PKCalpha (show PKCa Antibodies) and G3BP2 and that PKCalpha (show PKCa Antibodies) can phosphorylate G3BP2.
Wnt3a (show WNT3A Antibodies)-stimulated LRP6 (show LRP6 Antibodies) phosphorylation is dependent upon arginine methylation of G3BP2.
Probable scaffold protein that may be involved in mRNA transport (Potential).
ras GTPase-activating protein-binding protein 2
, Ras-GTPase activating protein SH3 domain-binding protein 2
, Ras GTPase-activating protein-binding protein 2
, GTPase activating protein (SH3 domain) binding protein 2
, GAP SH3 domain-binding protein 2
, Ras-GTPase-activating protein (GAP120) SH3-domain binding protein 2
, Ras-GTPase-activating protein (GAP<120>) SH3-domain binding protein 2