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anti-Human TUBA8 Antibodies:
anti-Mouse (Murine) TUBA8 Antibodies:
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Human Monoclonal TUBA8 Primary Antibody for ICC, FACS - ABIN969446
Abdollahi, Morrison, Sirey, Molnar, Hayward, Carr, Springell, Woods, Ahmed, Hattingh, Corry, Pilz, Stoodley, Crow, Taylor, Bonthron, Sheridan: Mutation of the variant alpha-tubulin TUBA8 results in polymicrogyria with optic nerve hypoplasia. in American journal of human genetics 2009
Show all 2 Pubmed References
Low TUBA8 expression is associated with 22q11.2 deletion syndrome.
Data provide evidence for a role of TUBA8 in hepatic fibrogenesis and malignancies making it a novel player in non-alcoholic steatohepatitis and hepatocellular carcinoma pathology.
TUBA8 can play a role in the regulation of cell growth, proliferation, and cell migration in a cell-specific manner in vitro.
TUBA8 is expressed at low levels in the developing human brain.
Mutation of the variant alpha-tubulin TUBA8 results in polymicrogyria with optic nerve hypoplasia.
Data (including data from studies conducted in knockout mice) suggest that Snta1 is involved in regulation of expression of Tuba8 in hepatocytes (but not in hepatic stellate cells); here, Snta1 protein levels are inversely related to Tuba8 protein expression in hepatocyte cell line. (Snta1 = syntrophin alpha-1; Tuba8 = tubulin alpha-8 chain)
Tuba8 is expressed at low levels in the developing mouse brain.
This gene encodes a member of the alpha tubulin protein family. Alpha tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. Mutations in this gene are associated with polymicrogyria and optic nerve hypoplasia. Alternate splicing results in multiple transcript variants.
alpha 4 tubulin
, tubulin alpha-4 chain
, tubulin, alpha 8
, tubulin alpha chain-like 2
, tubulin alpha-8 chain
, alpha tubulin 8
, alpha-tubulin 8
, tubulin alpha 8 L homeolog