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Here, the authors report that centrioles in delta-tubulin and epsilon-tubulin null mutant human cells lack triplet microtubules and fail to undergo centriole maturation.
EB1 recognizes the nucleotide state of tubulin in the microtubule lattice
This gene encodes a member of the tubulin superfamily. This protein localizes to the centriolar sub-distal appendages that are associated with the older of the two centrioles after centrosome duplication. This protein plays a central role in organization of the microtubules during centriole duplication. A pseudogene of this gene is found on chromosome 5.
tubulin epsilon chain
, tubulin, epsilon 1
, epsilon tubulin
, Epsilon tubulin
, tubulin epsilon chain-like
, epsilon-tubulin 1