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Cow (Bovine) Polyclonal ACOT2 Primary Antibody for WB - ABIN2775350
Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: Large-scale mapping of human protein-protein interactions by mass spectrometry. ... in Molecular systems biology 2007
the crystal structure at 2.1A resolution of human mitochondrial ACOT2, a type I enzyme is reported.
Data suggest that ACOT2 contributes to oxidation of fatty acids in liver mitochondria when demand for ATP is low and fatty acids are the prevailing substrate for energy metabolism; ACOT2 also contributes to prevention of fatty steatosis in liver.
This gene encodes a member of the acyl-CoA thioesterase protein family, and is one of four acyl-CoA hydrolase genes located in a cluster on chromosome 14. Alternative splicing results in multiple transcript variants.
acyl-CoA thioesterase 2
, peroxisomal long-chain acyl-coA thioesterase
, acyl-coenzyme A thioester hydrolase 2a
, acyl-coenzyme A thioesterase 2, mitochondrial
, long-chain acyl-CoA thioesterase 2
, mitochondrial acyl-CoA thioesterase 1
, peroxisomal long-chain acyl-coA thioesterase 2
, acyl coenzyme A thioester hydrolase
, very-long-chain acyl-CoA thioesterase