Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 Proteins

Protein Summary

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and is found associated with the sulfonylurea receptor SUR. Mutations in this gene are a cause of familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI), an autosomal recessive disorder characterized by unregulated insulin secretion. Defects in this gene may also contribute to autosomal dominant non-insulin-dependent diabetes mellitus type II (NIDDM), transient neonatal diabetes mellitus type 3 (TNDM3), and permanent neonatal diabetes mellitus (PNDM). Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

Alternative names and synonyms associated with Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11)

• potassium voltage-gated channel subfamily J member 11 (KCNJ11) antibody
• potassium inwardly-rectifying channel, subfamily J, member 11 (kcnj11) antibody
• potassium inwardly rectifying channel, subfamily J, member 11 (Kcnj11) antibody
• potassium voltage-gated channel subfamily J member 11 (Kcnj11) antibody

• BIR antibody
• HHF2 antibody
• IKATP antibody
• KIR6.2 antibody
• mBIR antibody
• Show all synonym aliases
• PHHI antibody
• TNDM3 antibody

Protein level used designations for KCNJ11

potassium inwardly-rectifying channel, subfamily J, member 11 , potassium inwardly-rectifying channel J11 , ATP-sensitive inward rectifier potassium channel 11 , ATP-sensitive inward rectifier potassium channel 11-like , inward rectifier K(+) channel Kir6.2 , BIR , potassium channel, inwardly rectifying subfamily J member 11 , potassium inwardly-rectifying channel subfamily J member 11 , IKATP , inward rectifier potassium channel Kir6.2 , beta-cell inward rectifier subunit , inwardly rectifying potassium channel KIR6.2 , potassium channel inwardly rectifing subfamily J member 11 , potassium inwardly rectifying channel, subfamily J, member 11 , ATP-sensitive inward rectifier potassium channel Kir6.2 , inwardly rectifying potassium channel Kir6.2