Browse our anti-Active BCR-Related (ABR) Antibodies

Full name:: anti-Active BCR-Related Antibodies (ABR)

On www.antibodies-online.com are 16 Active BCR-Related (ABR) Antibodies from 7 different suppliers available. Additionally we are shipping Active BCR-Related Kits (5) and Active BCR-Related Proteins (5) and many more products for this protein. A total of 28 Active BCR-Related products are currently listed.

Synonyms:: 6330400K15Rik, AU042359, MDB, xabr

list all antibodies	Gene Name	GeneID	UniProt
	ABR	29	Q12979
	ABR	109934	Q5SSL4
	ABR
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anti-Mouse (Murine) Antibodies:

5 WB Antibodies

anti-Rat (Rattus) Antibodies:

2 WB Antibodies

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Human Active BCR-Related (ABR) interaction partners

ABR depletion leads to G2/M accumulation in human embryonic stem cells. Centrosome dynamics and mitotic fidelity are compromised upon ABR depletion. When mitosis progresses without ABR, human embryonic stem cells show a high incidence of aneuploidy.
During vestibular morphogenesis, Abr and Bcr play complementary roles. Small Rho-related GTPases like Abr and Bcr are important for balance and motor coordination.

Mouse (Murine) Active BCR-Related (ABR) interaction partners

Loss of abr expression causes defects in spine development.
These results identify Abr-regulated CD4(+) T cell migration as an important component of severe cockroach allergen-evoked allergic asthma in mice.
Bcr and Abr play a critical role in down-regulating hypoxia-induced pulmonary hypertension by deactivating Rac1.
Abr and Bcr play important complementary roles during vestibular morphogenesis
These results identify Abr and Bcr as the only GTPase-activating proteins to date that specifically negatively regulate Rac function in vivo in primary macrophages.
These data show that Abr and Bcr normally curb very specific functions of mature tissue innate immune cells.

Active BCR-Related (ABR) Antigen Profile

Antigen Summary

This gene encodes a protein that is similar to the protein encoded by the breakpoint cluster region gene located on chromosome 22. The protein encoded by this gene contains a GTPase-activating protein domain, a domain found in members of the Rho family of GTP-binding proteins. Functional studies in mice determined that this protein plays a role in vestibular morphogenesis. Alternatively spliced transcript variants have been reported for this gene.

Alternative names and synonyms associated with Active BCR-Related (ABR)

active BCR-related (ABR) antibody
active BCR-related L homeolog (abr.L) antibody
active BCR-related gene (Abr) antibody

6330400K15Rik antibody
AU042359 antibody
MDB antibody
xabr antibody

Protein level used designations for ABR

active breakpoint cluster region-related protein

GENE ID	SPECIES
29	Homo sapiens
379901	Xenopus laevis
515556	Bos taurus
109934	Mus musculus

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