Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all synonyms
Select your origin of interest
Human p65 Protein expressed in HEK-293 Cells - ABIN2730698
Srinivasan, Blackburn, Lahiri: Functional characterization of a competitive peptide antagonist of p65 in human macrophage-like cells suggests therapeutic potential for chronic inflammation. in Drug design, development and therapy 2015
Show all 5 Pubmed References
Human p65 Protein expressed in Wheat germ - ABIN1317783
Ba, Bacsi, Luo, Aguilera-Aguirre, Zeng, Radak, Brasier, Boldogh: 8-oxoguanine DNA glycosylase-1 augments proinflammatory gene expression by facilitating the recruitment of site-specific transcription factors. in Journal of immunology (Baltimore, Md. : 1950) 2014
This study establishes p65 (show GORASP1 Proteins) as a novel target of IMP3 (show IGF2BP3 Proteins) in increasing glioma cell migration and underscores the significance of IMP3 (show IGF2BP3 Proteins)-p65 (show GORASP1 Proteins) feedback loop for therapeutic targeting in GBM.
TAB1 (show TAB1 Proteins) was identified as a functional target of miR (show MLXIP Proteins)-134, and the expression of TAB1 (show TAB1 Proteins) was increased by the transcription factors of NF-kappaB1 (show NFKB1 Proteins), c-Rel, and ELK1 (show ELK1 Proteins) via miR (show MLXIP Proteins)-134.
NOD2 up-regulates TLR2-mediated IL-23p19 (show IL23A Proteins) expression via increasing c-Rel activation in Paneth cell-like cells
Our study showed that PKCalpha (show PKCa Proteins) modulated cell resistance to apoptosis by stimulating NF-kappaB (show NFKB1 Proteins) activation and thus promoted the tumorigenesis of bladder cancer.
High NF-kappa-B (show NFKB1 Proteins) p65 (show GORASP1 Proteins) expression is associated with resistance to doxorubicin in breast cancer.
in colon cancer cell migration, activin utilizes NFkB to induce MDM2 (show MDM2 Proteins) activity leading to the degradation of p21 (show CDKN1A Proteins) in a PI3K (show PIK3CA Proteins) dependent mechanism
Studied melatonin's role in cell senescence, autophagy, sirtuin 1 (show SIRT1 Proteins) expression and acetylation of RelA in hydrogen peroxide treated SH-SY5Y cells.
The data demonstrate that miR (show MLXIP Proteins)-125b regulates nasopharyngeal carcinoma cell proliferation and apoptosis by targeting A20 (show TNFAIP3 Proteins)/NF-kappaB (show NFKB1 Proteins) signaling pathway, and miR (show MLXIP Proteins)-125b acts as oncogene (show RAB1A Proteins), whereas A20 (show TNFAIP3 Proteins) functions as tumor suppressor.
NF-kappaB (show NFKB1 Proteins) physically interacts with FOXM1 (show FOXM1 Proteins) and promotes transcription of FOXM1 (show FOXM1 Proteins) gene. NF-kappaB (show NFKB1 Proteins) directly binds FOXM1 (show FOXM1 Proteins) gene promoter. Silencing p65 (show GORASP1 Proteins) attenuates FOXM1 (show FOXM1 Proteins) and beta-catenin (show CTNNB1 Proteins) expression. NF-kappaB (show NFKB1 Proteins) activation is required for nuclear translocation of FOXM1 (show FOXM1 Proteins) and beta-catenin (show CTNNB1 Proteins). FOXM1 (show FOXM1 Proteins) and beta-catenin (show CTNNB1 Proteins) positively regulate NF-kappaB.Knockdown of beta-catenin (show CTNNB1 Proteins) and FOXM1 (show FOXM1 Proteins) downregulates p65 (show GORASP1 Proteins) protein and NF-kappaB (show NFKB1 Proteins)-dependent reporte...
Data show that protein kinase C epsilon (PKCepsilon (show PRKCE Proteins)) phosphorylates migration and invasion inhibitory protein (MIIP (show MIIP Proteins)) at Ser303 and promotes its binding to RelA/p65, facilitating colorectal cancer metastasis.
Hepatic SREBP-1c (show SREBF1 Proteins)-mediated lipid synthesis and the NF-kappaB (show NFKB1 Proteins) inflammatory pathway were both overinduced in cows with fatty liver.
Cytopathic bovine viral diarrhea virus strain induces immune marker production in bovine cells through the NF-kappaB (show NFKB1 Proteins) signaling pathway.
The role of NF-kappaB (show NFKB1 Proteins) and C/EBP (show CEBPA Proteins) factors in regulating basal and pathogen-induced expression of both genes from cattle, is investigated.
Altering the extracellular matrix to promote p38 (show MAPK14 Proteins) activation in cells on fibronectin (show FN1 Proteins) suppresses NF-kappaB (show NFKB1 Proteins) activation, suggesting a novel therapeutic strategy for treating
full length coding sequence of the cattle transcription factor p65 was isolated and cloned
the pathogen causing subclinical mastitis impairs NF-kappaB (show NFKB1 Proteins) activation in MEC (show CCL28 Proteins) thereby severely weakening the immune response,induction of IL-8 (show IL8 Proteins) and TNFalpha (show TNF Proteins), in the udder
These results confirm that VEGI (show TNFSF15 Proteins) utilizes NF-kappaB (show NFKB1 Proteins) as a pro-survival role factor in endothelial cells.
TMZ pretreatment effectively reduced the myocardial damage caused by CME via inhibiting the PDCD4 (show PDCD4 Proteins)/NF-kappaB (show NFKB1 Proteins)/ TNF-alpha (show TNF Proteins) pathway in cardiomyocytes.
Transmissible gastroenteritis virus infection activates NF-kappaB (show NFKB1 Proteins).
Zinc finger nuclease (show DCLRE1C Proteins) in-embryo editing of the RELA locus generated live born domestic pigs with the warthog RELA orthologue, associated with resilience to African Swine Fever.
SIRT1 (show SIRT1 Proteins), p53 (show TP53 Proteins) and NF-kappaB (show NFKB1 Proteins) are involved in the control of both the proliferation and the apoptosis of ovarian cells.
Porcine Coro1A (show CORO1A Proteins) is an important immunity related gene that helps to inhibit NF-kB activation during H. parasuis infection.
We propose that the variation in RELA identified between the warthog and domestic pig has the potential to underlie the difference between tolerance and rapid death upon African swine fever virus infection.
The characterization of porcine NF-kappaB (show NFKB1 Proteins) p65 (show SYT1 Proteins) subunit (pp65 (show LCP1 Proteins)), is reported.
Viral non-structural protein 1 suppressed host TNF-alpha (show TNF Proteins) promoter by inhibiting NF-kappaB (show NFKB1 Proteins) and Sp1 (show SP1 Proteins) promoter binding activity.
TLR4 (show TLR4 Proteins)-NF-kappaB (show NFKB1 Proteins) signal pathway is inhibited by paeonol in endotoxin-induced acute kidney injury
Type III secretion system of enteropathogenic Escherichia coli is necessary and sufficient for host NF-kappaB (show NFKB1 Proteins) activation.
TNF-alpha (show TNF Proteins) and the transcription factor nuclear factor kappa B (NF-kappaB (show NFKB1 Proteins)) p65 subunit were both upregulated in bleomycin-induced fibrotic lung tissue.
These findings suggested that USP14 induces NF-kappaB activity and ERK1/2 phosphorylation triggered by microbial infection.
this study demonstrates that phosphorylation of p65 serine 467 augment NF-kappaB (show NFKB1 Proteins) activity and exacerbates various deleterious effects of overnutrition in mice
RORalpha/gamma are important therapeutic targets for cutaneous inflammation; RORa (show RORA Proteins) and RORg (show RORC Proteins) have roles in inflammation in mouse models of atopic dermatitis and acute irritant dermititis
These findings identify differential requirements for the canonical NF-kappaB (show NFKB1 Proteins) subunits c-REL and RELA at distinct stages of mature B-cell development.
Expansion of myeloid-derived suppressor cells with aging in the bone marrow of mice through a Rela-dependent mechanism.
p65 expression correlates with elevated total cellular levels of STAT3 (show STAT3 Proteins) and STAT1 (show STAT1 Proteins) and supports activation of these transcription factors.
NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.
C-Rel proto-oncogene protein
, oncogene REL, avian reticuloendotheliosis
, proto-oncogene c-Rel
, v-rel reticuloendotheliosis viral oncogene homolog
, NF-kappa-B p65delta3
, nuclear factor NF-kappa-B p65 subunit
, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3
, transcription factor p65
, v-rel reticuloendotheliosis viral oncogene homolog A
, C-Rel protein
, NF-kappaB transcription factor p65 subunit
, v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65
, nuclear factor kappa B subunit p65
, avian reticuloendotheliosis viral (v-rel) oncogene homolog A
, p65 NF kappaB
, p65 NF-kappa B
, p65 NFkB
, NF-kB p65 subunit
, reticuloendotheliosis oncogene
, v-rel avian reticuloendotheliosis viral oncogene homolog
, LOW QUALITY PROTEIN: proto-oncogene c-Rel