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Full name:: SCY1-Like 1 (S. Cerevisiae) Proteins (SCYL1)

On www.antibodies-online.com are 5 SCY1-Like 1 (S. Cerevisiae) (SCYL1) Proteins from 4 different suppliers available. Additionally we are shipping SCYL1 Antibodies (38) and many more products for this protein. A total of 46 SCYL1 products are currently listed.

Synonyms:: 2810011O19Rik, C85140, DDBDRAFT_0189357, DDBDRAFT_0220502, DDB_0189357, DDB_0220502, GKLP, mdf, mfd, NKTL, Ntkl, p105, TAPK, TEIF, TRAP

list all proteins	Gene Name	GeneID	UniProt
	SCYL1	57410	Q96KG9
	SCYL1	78891	Q9EQC5
Rat SCYL1	SCYL1	293684	Q5M9F8
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Relevant Pathways for SCYL1 Proteins

p53 Signaling

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Human SCY1-Like 1 (S. Cerevisiae) (SCYL1) interaction partners

findings indicate that SCYL1 does not contribute to REST turnover and thus do not support a previous study suggesting a role for SCYL1 in mediating REST degradation
Disruptive SCYL1 mutations underlie a syndrome characterized by recurrent episodes of liver failure, peripheral neuropathy, cerebellar atrophy, and ataxia.
Data identified the large GTPase dynamin2 as an interacting protein of NTKL, which might be responsible for the phenotype alterations caused by NTKL overexpression, such as cytokinesis failure, increased cell motility and abnormal of cell division.
Data reveal that Scyl1 is a key organizer of a subset of the COPI machinery.
TEIF is a downstream effector in EGF/PI3K/Akt signaling.
TEIF as a novel MSP58-interacting protein.
suggested that the interaction of SCYL1BP1/Pirh2 could accelerate Pirh2 degradation through an ubiquitin-dependent pathway. SCYL1BP1 may function as an important tumor suppressor gene in HCC development
TEIF protein and centrosome amplification is commonly found in colorectal tumors. The expression level of TEIF is related to tumor histological grade and malignant degree.
Scyl1 interacts with 58K/formiminotransferase cyclodeaminase (FTCD) and golgin p115, and is required for the maintenance of Golgi morphology
Scyl1 participates in the nuclear aminoacylation-dependent tRNA export pathway.
SCYL1-BP1 can be ubiquitinated and degraded by Pirh2 but not by MDM2, which suggests that SCYL1-BP1 can be regulated by Pirh2.
NTKL is involved in centrosome-related cellular functions
Molecular cloning of telomerase transcriptional elements-interacting factor,(TEIF). TEIF may take part in the transcriptional activation of hTERT.
TEIF could specifically activate transcription of beta-pol promoter, but not that of DNA polymerase alpha or delta promoter. The responsible sequences for binding of TEIF were revealed
TEIF functions as a centrosome regulator. Its participation in DNA damage response, including telomere dysfunction and tumorigenesis.

Mouse (Murine) SCY1-Like 1 (S. Cerevisiae) (SCYL1) interaction partners

our results identify SCYL1 as a key regulator of motor neuron survival
Mutation in the Scyl1 gene encoding amino-terminal kinase-like protein causes a recessive form of spinocerebellar neurodegeneration.

SCYL1 Protein Profile

Protein Summary

This gene encodes a transcriptional regulator belonging to the SCY1-like family of kinase-like proteins. The protein has a divergent N-terminal kinase domain that is thought to be catalytically inactive, and can bind specific DNA sequences through its C-terminal domain. It activates transcription of the telomerase reverse transcriptase and DNA polymerase beta genes. The protein has been localized to the nucleus, and also to the cytoplasm and centrosomes during mitosis. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with SCYL1

N-terminal kinase-like protein (scy1)
N-terminal kinase-like protein (PITG_12105)
SCY1 like pseudokinase 1 (SCYL1)
N-terminal kinase-like protein (LOC592987)
SCY1-like, kinase-like 1 L homeolog (scyl1.L)
SCY1-like 1 (S. cerevisiae) (Scyl1)
SCY1 like pseudokinase 1 (Scyl1)

2810011O19Rik protein
C85140 protein
DDBDRAFT_0189357 protein
DDBDRAFT_0220502 protein
DDB_0189357 protein
DDB_0220502 protein
GKLP protein
mdf protein
mfd protein
NKTL protein
Ntkl protein
p105 protein
TAPK protein
TEIF protein
TRAP protein

Protein level used designations for SCYL1

SCY1 family protein kinase , N-terminal kinase-like protein , SCY1-like 1 (S. cerevisiae) , n-terminal kinase-like protein-like , SCY1-like protein 1 , coated vesicle-associated kinase of 90 kDa , likely ortholog of mouse N-terminal kinase-like protein , telomerase regulation-associated protein , telomerase transcriptional element-interacting factor , telomerase transcriptional elements-interacting factor , teratoma-associated tyrosine kinase , 105 kDa kinase-like protein , SCY1-like 1 splice variant 13 , SCY1-like 1 splice variant 15 , mitosis-associated kinase-like protein NTKL , ubiquitous protein kinase-like (105 kDa)

GENE ID	SPECIES
8615916	Dictyostelium discoideum AX4
9473115	Phytophthora infestans T30-4
466662	Pan troglodytes
483737	Canis lupus familiaris
592987	Strongylocentrotus purpuratus
716345	Macaca mulatta
100057036	Equus caballus
100460667	Pongo abelii
100606711	Nomascus leucogenys
443710	Xenopus laevis
57410	Homo sapiens
78891	Mus musculus
293684	Rattus norvegicus
515247	Bos taurus

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