Fragile Histidine Triad (FHIT) (C-Term) Peptide
FHIT
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all FHIT products
- FHIT (Fragile Histidine Triad (FHIT))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- KHVHVHVLPR KAGDFHRNDS IYEELQKHDK EDFPASWRSE EEMAAEAAAL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-FHIT Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- FHIT (Fragile Histidine Triad (FHIT))
- Background
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This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene.
Alias Symbols: FHIT,
Protein Size: 147 - Gene ID
- 2272
- NCBI Accession
- XP_005265010
- UniProt
- P49789
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