Actin-Like 6B (ACTL6B) (Middle Region) Peptide
ACTL6B
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all Actin-Like 6B (ACTL6B) products
- Actin-Like 6B (ACTL6B)
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- YMIAAKEPVR EGAPPNWKKK EKLPQVSKSW HNYMCNEVIQ DFQASVLQVS
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- ACTL6B Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Actin-Like 6B (ACTL6B)
- Background
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The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila, the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain. Alternative splicing results in multiple transcript variants.
Alias Symbols: ACTL6, BAF53B, arpNalpha
Protein Size: 426 - Gene ID
- 51412
- NCBI Accession
- NM_016188, NP_057272
- UniProt
- O94805
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