Mannosyl (Alpha-1,6-)-Glycoprotein beta-1,2-N-Acetylglucosaminyltransferase (MGAT2) Peptide
Quick Overview for Mannosyl (Alpha-1,6-)-Glycoprotein beta-1,2-N-Acetylglucosaminyltransferase (MGAT2) Peptide (ABIN936004)
Target
Origin
Source
Application
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Peptide Type
- Synthetic
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Sequence
- YAGLILFLEE DHYLAPDFYH VFKKMWKLKQ QECPECDVLS LGTYSASRSF
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of MGAT2 antibody,
Alternative Names: MGAT2 control peptide, MGAT2 antibody Blocking Peptide, Anti-MGAT2 Blocking Peptide, Mannosyl Blocking Peptide, Alpha 1-6-Glycoprotein Beta-1-2-N-Acetylglucosaminyltransferase Blocking Peptide, CDGS2 Blocking Peptide, GLCNACTII Blocking Peptide, GNT-II Blocking Peptide, GNT2 Blocking Peptide, MGAT2, MGAT-2, MGAT 2, MGAT-2 Blocking Peptide, MGAT 2 Blocking Peptide -
Purification
- The antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide is removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- MGAT2 (Mannosyl (Alpha-1,6-)-Glycoprotein beta-1,2-N-Acetylglucosaminyltransferase (MGAT2))
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Background
- MGAT2 is a Golgi enzyme catalyzing an essential step in the conversion of oligomannose to complex N-glycans. The enzyme has the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain, and a C-terminal catalytic domain. Mutations in its gene may lead to carbohydrate-deficient glycoprotein syndrome, type II. The product of this gene is a Golgi enzyme catalyzing an essential step in the conversion of oligomannose to complex N-glycans.
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Molecular Weight
- 51 kDa
Target
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