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F-Box Protein 7 (FBXO7) (Middle Region) Peptide

FBXO7 Reactivity: Human Host: Synthetic BP, WB, IP
Catalog No. ABIN976761
  • Target See all FBXO7 products
    FBXO7 (F-Box Protein 7 (FBXO7))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 2
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunoprecipitation (IP)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-FBXO7 antibody (Catalog #: ARP43128_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    FBXO7 (F-Box Protein 7 (FBXO7))
    Background
    FBXO7 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXO7 belongs to the Fbxs class and it may play a role in regulation of hematopoiesis.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it may play a role in regulation of hematopoiesis. Alternatively spliced transcript variants of this gene have been identified with the full-length natures of only some variants being determined.

    Alias Symbols: DKFZp686B08113, FBX, FBX07, FBX7, PKPS, PARK15

    Protein Interaction Partner: SKP1,SKP1,BIRC3,ELF4,SKP1,CDC34,CDK6,COPS6,CUL1,PSMF1,SKP1,UBE2D2

    Protein Size: 522
    Molecular Weight
    58 kDa
    Gene ID
    25793
    NCBI Accession
    NM_012179, NP_036311
    UniProt
    Q9Y3I1
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