Histone Deacetylase 1 (HDAC1) (Middle Region) Peptide
HDAC1
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all HDAC1 products
- HDAC1 (Histone Deacetylase 1 (HDAC1))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-HDAC1 antibody (Catalog #: ARP32358_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- HDAC1 (Histone Deacetylase 1 (HDAC1))
- Background
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Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. HDAC1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DKFZp686H12203, GON-10, HD1, RPD3, RPD3L1
Protein Interaction Partner: BCL3,BRCA1,CDKN1A,CDKN1A,DNMT3B,ESR1,HDAC9,MBD3,MT1G,NFKBIA,RARB,RB1,RB1,RBBP4,RECQL4,RUNX1T1,RUVBL2,SIN3A,STAT3,TNFSF10,ZBTB16,APEX1,AR,ARID4A,ATRX,BAZ2A,BCL3,BCOR,BRCA1,BRMS1,BRMS1L,BUB1,BUB1B,BUB3,CBFA2T3,CDC20,CDH1,CDYL,CHD1,CHD4,CREBBP,CSNK2A1,CSNK2A2,CTBP1,DAXX,DDB2,DDX17,DHX30,DNMT1,DNMT3A,DNMT3B,DNMT3L,EED,EID2,EID2B,EZH2,FKBP3,FOXG1,GCM1,HBP1,HDAC1,HDAC2,HDAC3,HDAC9,HEY2,HIC1,HIF1A,HIF1AN,HR,HUS1,IKZF1,ING1,KAT5,KDM1A,KLF11,MAD1L1,MAGEA1,MBD2,MBD3,MDM2,MECOM,MECOM,MIER1,MORF4L2,MTA1,MYOD1,NCOR2,NFE4,NFKB1,NFKBIA,NR2E3,NR2F2,NRIP1,PCNA,PEX14,PHB,PHB2,PHF12,PHF21A,PIAS3,PIAS4,PITX2,PML,PPARD,PPP2R1B,PTMA,RAD9A,RAP1A,RB1,RBBP4,RBBP7,RBL1,RBL2,RBP1,RBPJ,RELA,RFC1,RFC4,RUNX1T1,RUNX3,RUVBL2,SALL1,SAP18,SAP30,SATB1,SENP1,SETDB1,SIN3A,SIN3B,SMAD2,SP1,SP3,SPEN,STAT2,STAT3,SUDS3,SUV39H1,TAL1,TGIF1,TGIF2,TOP2A,TOP2B,TP53,TPD52L1,TRIM27,TXNIP,UBE2I,ZBTB16,ZNF76,APBB1,AR,ARID4B,ATR,BCL6,BCOR,BNIP3,BRCA1,BUB1,BUB1B,BUB3,CABIN1,CBFA2T3,CBX5,CDC20,CDH1,CDKN1A,CDYL,CHD1,CHD3,CHD4,CTBP1,DAXX,DDX17,DDX5,DNMT1,DNMT3A,DNMT3B,DNMT3L,DZIP3,Dnmt1,E2F1,E2F4,EED,EFCAB6,ETHE1,EZH2,FKBP3,FRA10F,Foxg1,GATA1,GATAD2B,GLI1,GLI2,GTF2I,H2AFY,HBP1,HCFC1,HDAC1,HDAC2,HDAC9,HEY2,HIF1A,HIF1AN,HINFP,HMG20B,HR,HSPA4,HSPD1,HUS1,IFRD1,IKZF1,ING1,ING2,KCTD11,KDM1A,KDM5C,KLF11,MAD1L1,MBD2,MBD3,MBD3L1,MBD4,MDM2,MECOM,MECP2,MIER1,MLL,MTA1,MTA2,MXD1,MYOD1,NCOR2,NFIX,NFKB1,NR2F2,Nrip1,PADI4,PCNA,PHB,PHF12,PHF21A,PML,PPARD,PRDM1,PTMA,RAD9A,RB1,RBBP4,RBBP7,RBL1,RBL2,RCOR1,RELA,REST,RFC1,RUNX1T1,SAP130,SAP30,SATB1,SFPQ,SIN3A,SIN3B,SMAD2,SMARCA2,SMARCB1,SP1,SP3,SPEN,SPI1,SUDS3,SUV39H1,TAB2,TAL1,TGIF1,TGIF2,TLE4,TOP2A,TOP2B,TP53,TPD52L1,TXNIP,UHRF1,VHL,WHSC1,YY1,ZBTB16,ZMYM2,ZMYND11
Protein Size: 482 - Molecular Weight
- 55 kDa
- Gene ID
- 3065
- NCBI Accession
- NM_004964, NP_004955
- UniProt
- Q13547
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