Mitogen-Activated Protein Kinase 1 (MAPK1) (C-Term) Peptide
MAPK1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all ERK2 (MAPK1) products
- ERK2 (MAPK1) (Mitogen-Activated Protein Kinase 1 (MAPK1))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- PYLEQYYDPS DEPIAEAPFK FDMELDDLPK EKLKELIFEE TARFQPGYRS
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-MAPK1 Antibody(ARP58899_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ERK2 (MAPK1) (Mitogen-Activated Protein Kinase 1 (MAPK1))
- Background
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The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.
Alias Symbols: ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk
Protein Interaction Partner: DAPK1,MAP3K1,MBP,RAF1,RPS6KA2,TNIP1,TSC2,VAV1,MAP2K1,MAP2K2,AR,ARRB1,ARRB2,BCL2,BCL6,BRAF,C1QBP,CAD,CALCOCO1,CASP8,CASP9,CAV1,CD19,CDX2,CEBPB,CEP55,CMTM3,CSDA,DAPK1,DUSP1,DUSP16,DUSP2,DUSP3,DUSP4,DUSP5,DUSP6,DUSP7,DUSP9,DYRK1B,EGFR,EIF4EBP1,ELK1,EPOR,ERF,
Protein Size: 360 - Molecular Weight
- 41 kDa
- Gene ID
- 5594
- NCBI Accession
- NM_138957, NP_620407
- UniProt
- P28482
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