RAE1 RNA Export 1 Homolog (S. Pombe) (RAE1) Peptide
RAE1
Reactivity: Human
Host: Synthetic
BP, IHC, WB
Catalog No. ABIN982621
Quick Overview for RAE1 RNA Export 1 Homolog (S. Pombe) (RAE1) Peptide (ABIN982621)
Target
RAE1
(RAE1 RNA Export 1 Homolog (S. Pombe) (RAE1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-RAE1 antibody (Catalog #: ARP40302_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RAE1 (RAE1 RNA Export 1 Homolog (S. Pombe) (RAE1))
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Background
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RAE1 is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton.Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
Alias Symbols: MIG14, MRNP41, Mnrp41, dJ481F12.3, dJ800J21.1
Protein Interaction Partner: BUB1,DDX24,KLRC4,NUP98,NXF1,AGGF1,ARMC8,ATE1,BUB1,Bub1,COPS6,COPS8,CS,DDX19B,FAF1,FAM122B,HSP90B1,KLRK1,MAGED4B,MAP1B,MIOS,MPST,MYCBP2,NUP188,NUP214,NUP62,NUP88,NUP93,NUP98,NUPL2,POLA1,POLA2,POLR3A,POLR3B,POLR3E,POLR3H,PRIM1,PRIM2,PRKD2,PRKD3,RBM8A,SART1,SEH1L,SF3A1,SF3A2,SF3A3,SFN,SMC1A,SMC3,SMU1,TJP1,TJP2,UFD1L,USP11,USP7,WDR24,WDR26,WDR59,WDR75
Protein Size: 368 -
Molecular Weight
- 40 kDa
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Gene ID
- 8480
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NCBI Accession
- NM_001015885, NP_001015885
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UniProt
- P78406
Target
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