BIM ELISA Kits

Protein Summary

The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X(L), and MCL1, and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified.

Alternative names and synonyms associated with BIM (BCL2L11)

• BCL2-like 11 (bcl2l11) antibody
• BCL2 like 11 (BCL2L11) antibody
• BCL2-like 11 (apoptosis facilitator) (Bcl2l11) antibody
• BCL2 like 11 (Bcl2l11) antibody

• 1500006F24Rik antibody
• BAM antibody
• Bim antibody
• BIMEL antibody
• BimL antibody
• Show all synonym aliases
• Bod antibody

Protein level used designations for BCL2L11

BCL2-like 11 , Bcl-2 interacting mediator of cell death , bcl-2 interacting mediator of cell death , bcl-2 interacting protein Bim , bcl-2-like protein 11 , bcl-2-related ovarian death agonist , Bcl2 interacting mediator of cell death , bcl2-L-11 , bcl2-interacting mediator of cell death , Bcl-2 related apoptotic gene product BimL , bcl-2-related ovarian death protein