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anti-Human PPP2R3B Antibodies:
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Cow (Bovine) Polyclonal PPP2R3B Primary Antibody for WB - ABIN2775379
Stevens, Janssens, Martens, Dilworth, Goris, Van Hoof: Identification and characterization of B\-subunits of protein phosphatase 2 A in Xenopus laevis oocytes and adult tissues." in European journal of biochemistry / FEBS 2003
Show all 2 Pubmed References
PPP2R3B codes for the PR70 protein, a regulatory substrate-recognizing subunit of protein phosphatase 2A. PR70 decreased melanoma growth by negatively interfering with DNA replication and cell cycle progression through its role in stabilizing CDC6 (show CDC6 Antibodies)-chromatin licensing and CDT1 (show CDT1 Antibodies) interaction
Results show the crystal structure of PR48/PR70, at 2.0 A degrees resolution with two domain elongated structure and two Ca2 (show CA2 Antibodies)+ binding EF-hands Scattering data.
Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B'' family. The B'' family has been further divided into subfamilies. The product of this gene belongs to the beta subfamily of regulatory subunit B''.
, PP2A, subunit B, PR48 isoform
, protein phosphatase 2 (formerly 2A), regulatory subunit B'', beta
, serine/threonine protein phosphatase 2A, 48kDa regulatory subunit B
, serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta
, PP2A B'' subunit PR48
, uncharacterized protein LOC682033