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Recommendations are based on data provided indicating:
ELISA Kit Sensitivity
The recommended ELISA Kit will likely detect the antigen better in the approved sample types than the available alternatives.
ELISA Kit Specificity
The recommended ELISA Kit will likely detect the antigen in question with higher specificity in approved samples than the available alternatives.
The results will be likely more reproducible, with high inter- or intra-assay CV and Recovery (for values within the std curve) than the available alternatives.
ELISA Kit Robustness
The recommended assay will likely function better with approved sample types, and will not suffer from undue matrix interference than the available alternatives.
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CRH Antigen Profile
Corticotropin-releasing hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in this protein has been observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturition.
Alternative names and synonyms associated with CRH
corticotropin releasing hormone (Crh) ELISA Kit
corticotropin releasing hormone (CRH) ELISA Kit
corticotropin releasing hormone b (crhb) ELISA Kit
corticotropin releasing hormone (crh) ELISA Kit
corticotropin releasing hormone S homeolog (crh.S) ELISA Kit
corticotropin releasing hormone L homeolog (crh.L) ELISA Kit