Browse our anti-GABBR1 (GABBR1) Antibodies

Full name:: anti-gamma-aminobutyric Acid (GABA) B Receptor, 1 Antibodies (GABBR1)

On www.antibodies-online.com are 189 gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1) Antibodies from 26 different suppliers available. Additionally we are shipping GABBR1 Proteins (11) and GABBR1 Kits (4) and many more products for this protein. A total of 211 GABBR1 products are currently listed.

Synonyms:: bM573K1.1, dJ271M21.1.1, dJ271M21.1.2, GABA(B)R1, GABAB1, GABAbR1, GABBR1, GABBR1-3, GB1, GPRC3A

list all antibodies	Gene Name	GeneID	UniProt
	GABBR1	2550	Q9UBS5
	GABBR1	81657	Q9Z0U4
	GABBR1	54393	Q9WV18
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Top referenced anti-GABBR1 Antibodies

Mammalian Monoclonal GABBR1 Primary Antibody for ISt, IHC - ABIN1304650 : Karls, Mynlieff: GABAB receptors couple to Gαq to mediate increases in voltage-dependent calcium current during development. in Journal of neurochemistry 2015 (PubMed)
Show all 8 Pubmed References
Human Monoclonal GABBR1 Primary Antibody for IF, RNAi - ABIN560976 : Tse, Su, Chang, Tsang, Yu, Tang, See, Hsueh, Yang, Hao, Li, Wang, Liao, Chen, Lin, Jorgensen, Chang, Shugart: Genome-wide association study reveals multiple nasopharyngeal carcinoma-associated loci within the HLA region at chromosome 6p21.3. in American journal of human genetics 2009 (PubMed)
Show all 4 Pubmed References
Human Polyclonal GABBR1 Primary Antibody for WB - ABIN152505 : Fatemi, Folsom, Reutiman, Thuras: Expression of GABA(B) receptors is altered in brains of subjects with autism. in Cerebellum (London, England) 2009 (PubMed)
Show all 3 Pubmed References
Cow (Bovine) Polyclonal GABBR1 Primary Antibody for WB - ABIN2473736 : Bowery, Bettler, Froestl, Gallagher, Marshall, Raiteri, Bonner, Enna: International Union of Pharmacology. XXXIII. Mammalian gamma-aminobutyric acid(B) receptors: structure and function. in Pharmacological reviews 2002 (PubMed)

More Antibodies against GABBR1 Interaction Partners

Human gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1) interaction partners

There was no statistically significant association for the two SNPs of the GABBR1 gene (rs29230 and rs29267). However, a significant difference between AUD individuals and controls was observed at genotype level for rs2900512 of GABBR2 (show GABBR2 Antibodies) gene.
The combined analysis confirmed evidence of genome-wide significant associations in the Han Chinese population for three loci, at 2p16.1 (rs1051061, in an exon of VRK2, P=1.14 x 10-12, odds ratio (OR)=1.17), 6p22.1 (rs115070292 in an intron of GABBR1, P=4.96 x 10-10, OR=0.77) and 10q24.32 (rs10883795 in an intron of AS3MT, P=7.94 x 10-10, OR=0.87; rs10883765 at an intron of ARL3, P=3.06 x 10-9, OR=0.87).
Genotype and allele frequencies of rs29230 in GABR1 were significantly different between cases and controls, especially for male patients, for obstructive sleep apnea risk in Chinese Han population.
presynaptic gamma-aminobutyric acid type B receptor deficits contribute to altered neuronal excitability in fragile X (show FMR1 Antibodies) syndrome
Results show that GABBR1 minor genotypes/alleles were protective against risk for alcoholism in 3 ethnically diverse cohorts.
Cell surface ubiquitination precedes endocytosis, after which USP14 acts as an ubiquitin-binding protein that targets the ubiquitinated GABA B receptor to lysosomal degradation and promotes its deubiquitination.
GABA(B)R stimulation promotes chemotaxis in RBL cells which is dependent on signaling via PI3-K/Akt, Src kinases and on rearrangement of both microtubules and actin cytoskeleton.
GABBR1 receptors are expressed in aortic smooth muscle cells and regulate the [Ca(2 (show CA2 Antibodies)+)]i via a Gi/o-coupled receptor pathway and a phospholipase C (show PLC Antibodies) activation pathway.
GABBR1 protein involved in phenylthiourea bitter taste detection.
Authors suggest GABBR1, GABA receptor B1, is implicated in schizophrenia based on a Human endogenous retrovirus long terminal repeat (HERV-W LTR) in the regulatory region of GABBR1.

Mouse (Murine) gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1) interaction partners

These data suggest that GABA, acting through both presynaptic GABAA (show GABRg1 Antibodies) and GABAB receptors, modulate the amplitude and short-term plasticity of excitatory synapses, a result not possible from activation of either receptor type alone
presynaptic gamma-aminobutyric acid type B receptor deficits contribute to altered neuronal excitability in fragile X (show FMR1 Antibodies) syndrome
These results suggest a role for GABAB receptor in Fmrp (show FMR1 Antibodies) regulation and a potential interest of GABAB receptor signaling in Fragile X (show FMR1 Antibodies) syndrome improvement.
Activation of GABA(B) or mGlu2 (show GRM2 Antibodies)/3 receptors inhibited both evoked presynaptic Ca(2 (show CA2 Antibodies)+) transients and striatal field potentials.
Immunoblotting and RT-PCR results showed that NIHL increased the expression of PKCgamma (show PRKCG Antibodies) but decreased that of GABABR1 and GABABR2 (show GABBR2 Antibodies) at both protein and mRNA levels in the CNC
GABAB(1) receptor subunit isoforms differentially regulate the deleterious effects of stress and, thus, may be important therapeutic targets for the treatment of depression
Results establish an endogenous GABA/GABAB1 feedback mechanism that keeps TRPV1 (show TRPV1 Antibodies)-mediated pain hypersensitivity in check.
The Gabbr1 has an important role in mediating the anxiety-related effects induced by nicotine.
Sex differences in reproductive genes Gnrh1 (show GNRH1 Antibodies), Gad1 (show GAD1 Antibodies), and Kiss1 (show KISS1 Antibodies) are critically disturbed in GABAB1-deficient mice, probably altering the organization and development of neural circuits governing the reproductive axis.
GABAB signaling may normally directly or indirectly inhibit Kiss1 (show KISS1 Antibodies) expression, particularly in the bed nucleus of the stria terminalis and medial amygdala

GABBR1 Antigen Profile

Antigen Summary

Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic

Alternative names and synonyms associated with GABBR1

gamma-aminobutyric acid type B receptor subunit 1 (GABBR1) antibody
gamma-aminobutyric acid (GABA) B receptor, 1a (gabbr1a) antibody
gamma-aminobutyric acid (GABA) B receptor, 1 (gabbr1) antibody
gamma-aminobutyric acid type B receptor subunit 1 (Gabbr1) antibody
gamma-aminobutyric acid (GABA) B receptor, 1 (GABBR1) antibody
gamma-aminobutyric acid (GABA) B receptor, 1 (Gabbr1) antibody

bM573K1.1 antibody
dJ271M21.1.1 antibody
dJ271M21.1.2 antibody
GABA(B)R1 antibody
GABAB1 antibody
GABAbR1 antibody
GABBR1 antibody
GABBR1-3 antibody
GB1 antibody
GPRC3A antibody

Protein level used designations for GABBR1

GABA-BR1 , GABAB, subunit 1c , gamma-aminobutyric acid type B receptor subunit 1 , seven transmembrane helix receptor , gamma-aminobutyric acid (GABA) B receptor, 1 , gaba1 , gamma-aminobutyric acid (GABA) B receptor 1 , gamma-aminobutyric acid B receptor 1 , GABA-B receptor 1 , GABA-B-R1 , GABABR1 , gb1 , GABA-BR1b receptor , bM573K1.1.1 (gamma-aminobutyric acid (GABA) B receptor, 1a) , gamma-aminobutyric acid (GABA-B) receptor, 1

GENE ID	SPECIES
2550	Homo sapiens
373873	Danio rerio
471946	Pan troglodytes
488340	Canis lupus familiaris
513785	Bos taurus
708987	Macaca mulatta
100135080	Xenopus (Silurana) tropicalis
100141417	Sus scrofa
100170763	Cavia porcellus
100172928	Pongo abelii
81657	Rattus norvegicus
54393	Mus musculus

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Show all anti-gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1) Antibodies with Pubmed References

Human gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1) interaction partners

Mouse (Murine) gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1) interaction partners

Antigen Summary

Alternative names and synonyms associated with GABBR1

Protein level used designations for GABBR1