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anti-Rat (Rattus) BCLAF1 Antibodies:
anti-Mouse (Murine) BCLAF1 Antibodies:
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Human Polyclonal BCLAF1 Primary Antibody for ICC, IF - ABIN151225
Liu, Lu, Miki, Yoshida: Protein kinase C delta induces transcription of the TP53 tumor suppressor gene by controlling death-promoting factor Btf in the apoptotic response to DNA damage. in Molecular and cellular biology 2007
Show all 4 Pubmed References
Human Monoclonal BCLAF1 Primary Antibody for IF, WB - ABIN968645
Kasof, Goyal, White: Btf, a novel death-promoting transcriptional repressor that interacts with Bcl-2-related proteins. in Molecular and cellular biology 1999
Constitutive expression of the anti-apoptotic molecule Bfl1 (show BCL2A1 Antibodies) (A1) in murine vascular Endothelial Cells leads to prolonged allograft survival due to modifying inflammation.
Bclaf1 facilitates the differentiation of early retinal precursors into retinal ganglion cells, amacrine cells, and horizontal cells rather than into cone photoreceptors.
Sirt1 (show SIRT1 Antibodies) negatively regulates T cell activation via H3K56 deacetylation at the promoter region to inhibit transcription of Bclaf1
Bclaf1 expression was found to be strongly upregulated during the saccular stage of murine embryonic lung development and was dispensable for thymocyte development.
LTBR (show LTBR Antibodies) and BCLAF1 showed higher DNA methylation (show HELLS Antibodies) percentages in the marsupialized OKCs, but this difference did not affect gene expression (P > .05).
Results indicate a role for the RNA processing factors THRAP3 (show THRAP3 Antibodies) and BCLAF1 in the regulation of the cellular DNA damage response (DDR (show DDR1 Antibodies)) pathway.
findings link treatment responsiveness to re-instatement of miR (show MLXIP Antibodies)-194-5p/BCLAF1 balance
SMYD3 (show SMYD3 Antibodies) physically interacts with the promoter of BCLAF1 and upregulates its expression by accumulating di- and trimethylation of H3K4 at the BCLAF1 locus. BCLAF1 depletion inhibits SMYD3 (show SMYD3 Antibodies)-induced autophagy.
The Bclaf1 can interact with the leucine zipper region of C/EBPbeta (show CEBPB Antibodies) and cooperate with C/EBPbeta (show CEBPB Antibodies) to upregulate IL-8 (show IL8 Antibodies).
both cytoplasmic BCLAF1 expression and nuclear BCLAF1 expression are increased in post-neoadjuvant therapy rectal cancer, and that negative and weak nuclear BCLAF1 expression are independently associated with a poor prognosis
SRSF10 (show SRSF10 Antibodies) is a key regulator of BCLAF1 pre-mRNA splicing and the maintenance of oncogenic features in human colon cancer cells
findings showed that FXR1P (show FXR1 Antibodies) interacts with BTF in vivo and proved that FXR1P (show FXR1 Antibodies) and BTF can co-localize mainly in the cytoplasm around the nucleus
BTF has functions distinct from TRAP150 (show THRAP3 Antibodies) in regulating the subcellular distribution of mRNAs in human cells.
BCLAF1 co-localized with gammaH2AX (show H2AFX Antibodies) foci in nuclei and stabilized the Ku70 (show XRCC6 Antibodies)/DNA-PKcs (show PRKDC Antibodies) complex therein, facilitating non-homologous end joining (NHEJ)-based DSB repair in surviving cells.
This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.
bcl-2-associated transcription factor 1
, mitochondrial fission regulator 2
, protein FAM54A
, BCL2-associated transcription factor 1