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anti-Human FOXM1 Antibodies:
anti-Rat (Rattus) FOXM1 Antibodies:
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Human Polyclonal FOXM1 Primary Antibody for ChIP, ICC - ABIN441006
Zhao, Siu, Jiang, Tam, Ngan, Le, Wong, Wong, Gomes, Bella, Khongkow, Lam, Cheung: Overexpression of forkhead box protein M1 (FOXM1) in ovarian cancer correlates with poor patient survival and contributes to paclitaxel resistance. in PLoS ONE 2014
Show all 2 Pubmed References
Human Polyclonal FOXM1 Primary Antibody for IF (p), IHC (p) - ABIN749138
Liu, Zhang, Mao, Zhang, Zhang: Over-expression of FoxM1 is associated with adverse prognosis and FLT3-ITD in acute myeloid leukemia. in Biochemical and biophysical research communications 2014
Dog (Canine) Polyclonal FOXM1 Primary Antibody for WB - ABIN2781166
Laoukili, Alvarez, Meijer, Stahl, Mohammed, Kleij, Heck, Medema: Activation of FoxM1 during G2 requires cyclin A/Cdk-dependent relief of autorepression by the FoxM1 N-terminal domain. in Molecular and cellular biology 2008
Show all 2 Pubmed References
Results demonstrated that miR (show MLXIP Antibodies)-216b is a tumor suppressor in melanoma, identified the FOXM1 signaling pathway as a target of miR (show MLXIP Antibodies)-216b action.
Authors showed that RFC5 (show RFC5 Antibodies) expression is positively correlated with FoxM1 expression in human glioma cells and FoxM1 is able to transcriptionally activate RFC (show RFC1 Antibodies) expression by interaction with the RFC5 (show RFC5 Antibodies) promoter.
NF-kappaB (show NFKB1 Antibodies) physically interacts with FOXM1 and promotes transcription of FOXM1 gene. NF-kappaB (show NFKB1 Antibodies) directly binds FOXM1 gene promoter. Silencing p65 (show GORASP1 Antibodies) attenuates FOXM1 and beta-catenin (show CTNNB1 Antibodies) expression. NF-kappaB (show NFKB1 Antibodies) activation is required for nuclear translocation of FOXM1 and beta-catenin (show CTNNB1 Antibodies). FOXM1 and beta-catenin (show CTNNB1 Antibodies) positively regulate NF-kappaB.Knockdown of beta-catenin (show CTNNB1 Antibodies) and FOXM1 downregulates p65 (show GORASP1 Antibodies) protein and NF-kappaB (show NFKB1 Antibodies)-dependent reporte...
FOXM1 expression in solid tumor tissues is associated with poor survival in most solid tumors, which suggests that FOXM1 is a valuable prognostic biomarker and a promising therapeutic target for solid tumors.
FOXM1 is up-regulated in all three major EOCs subtypes, and is a prognostic biomarker and a potential combinatorial therapeutic target in platinum resistant disease, irrespective of tumor histology.
Authors demonstrated that inhibition of either FOXM1 or AGR2 (show AGR2 Antibodies) in human PIMAs inhibited mucinous characteristics, and reduced tumor growth and invasion. FOXM1 is necessary and sufficient to induce mucinous phenotypes in lung tumor cells in vivo.
we hypothesize that FOXM1 regulates radioresistance via STAT3 (show STAT3 Antibodies) in GBM cells. We also, show GBM patients with high FOXM1 expression have poor prognosis.
FOXM1 promotes 5-FU resistance by up-regulating ABCC10 (show ABCC10 Antibodies) expression in colorectal tumor cells.
Findings provide a novel understanding of the mechanism of gastric cancer and highlight the important role of BTF3 (show BTF3 Antibodies)/FOXM1 in tumor growth and BTF3 (show BTF3 Antibodies)/JAK2 (show JAK2 Antibodies)/STAT3 (show STAT3 Antibodies) in EMT (show ITK Antibodies) and metastasis
FOXM1 bound directly to the GLUT1 (show SLC2A1 Antibodies) and HK2 (show HK2 Antibodies) promoter regions and regulated the promoter activities and the expression of the genes at the transcriptional level. This reveals a novel mechanism by which glucose metabolism is regulated by FOXM1.
Upregulated ROS (show ROS1 Antibodies) induced by FABP4 (show FABP4 Antibodies) was of significance in activating FoxM1 leading to airway inflammation and epithelial barrier dysfunction.
Interactions between the Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) and the Kras/ERK (show EPHB2 Antibodies)/Foxm1 pathways are essential to restrict SOX9 (show SOX9 Antibodies) expression in basal cells during pulmonary branching morphogenesis
YAP (show YAP1 Antibodies) cooperates with FOXM1 to contribute to chromosome instability in hepatocellular carcinoma.
RCM-1 (show TNNI3 Antibodies) blocked the nuclear localization and increased the proteasomal degradation of Forkhead box M1 (FOXM1), a transcription factor critical for the differentiation of goblet cells from airway progenitor cells.
These data implicate the insulin (show INS Antibodies)-FoxM1/PLK1 (show PLK1 Antibodies)/CENP-A (show CENPA Antibodies) pathway-regulated mitotic cell-cycle progression as an essential component in the beta cell adaptation to delay and/or prevent progression to diabetes.
EGF (show EGF Antibodies) promotes FoxM1 expression through the ERK (show EPHB2 Antibodies) signal pathway
FoxM1 induction in the pulmonary vasculature was inhibited by a p110gamma (show PIK3CG Antibodies)-selective inhibitor and in Pik3cg (show PIK3CG Antibodies)(-/-) mice after LPS (show TLR4 Antibodies) challenge. Defective vascular repair in Pik3cg (show PIK3CG Antibodies)-/- mice results from impaired FoxM1 expression
we suggest that proper regional decidualization and polyploidy development requires FoxM1 signaling downstream of Hoxa10 (show HOXA10 Antibodies) and cyclin D3 (show CCND3 Antibodies).
FOXM1 and CENPF (show CENPF Antibodies) are master regulators of prostate cancer malignancy, and can serve as drug response markers for antineoplastic drugs efficiency.
Both gain-of-function and loss-of-function TP53 (show TP53 Antibodies) mutations contribute to overexpression of FoxM1 in high-grade serous ovarian cancer.
the sequence and expression pattern of FoxM1 (fork head box M1) transcription factor in Xenopus laevis embryos are described
Results suggest that FoxM1 functions to link cell division and neuronal differentiation in early Xenopus embryos.
The protein encoded by this gene is a transcriptional activator involved in cell proliferation. The encoded protein is phosphorylated in M phase and regulates the expression of several cell cycle genes, such as cyclin B1 and cyclin D1. Several transcript variants encoding different isoforms have been found for this gene.
Forkhead, drosophila, homolog-like 16
, HNF-3/fork-head homolog 11
, M-phase phosphoprotein 2
, MPM-2 reactive phosphoprotein 2
, forkhead box protein M1
, forkhead-related protein FKHL16
, hepatocyte nuclear factor 3 forkhead homolog 11
, transcription factor Trident
, winged-helix factor from INS-1 cells
, INS-1 winged helix
, forkhead box M1
, forkhead box protein M1-like
, forkhead homolog 16
, winged-helix transcription factor Trident