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CCNDBP1 Protein (His tag)

CCNDBP1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2713325
  • Target See all CCNDBP1 Proteins
    CCNDBP1 (Cyclin D-Type Binding-Protein 1 (CCNDBP1))
    Protein Type
    Recombinant
    Origin
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 4
    • 2
    • 2
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This CCNDBP1 protein is labelled with His tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human CCNDBP1 (full length, N-term HIS tag, transcript variant 1) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product CCNDBP1 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the N-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 100 mM Arg. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    CCNDBP1 (Cyclin D-Type Binding-Protein 1 (CCNDBP1))
    Alternative Name
    Ccndbp1 (CCNDBP1 Products)
    Synonyms
    CCNDBP1 Protein, dip1 Protein, gcip Protein, DIP1 Protein, GCIP Protein, HHM Protein, AU022347 Protein, Maid Protein, SECC-8 Protein, SSEC-8 Protein, cyclin D1 binding protein 1 Protein, cyclin D-type binding-protein 1 Protein, CCNDBP1 Protein, ccndbp1 Protein, Ccndbp1 Protein
    Background
    This gene was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Several alternatively spliced variants have been found for this gene.
    Molecular Weight
    40.3 kDa
    NCBI Accession
    NP_036274
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