CCNDBP1 Protein (His tag)
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- Target See all CCNDBP1 Proteins
- CCNDBP1 (Cyclin D-Type Binding-Protein 1 (CCNDBP1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CCNDBP1 protein is labelled with His tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human CCNDBP1 (full length, N-term HIS tag, transcript variant 1) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product CCNDBP1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the N-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 100 mM Arg. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- CCNDBP1 (Cyclin D-Type Binding-Protein 1 (CCNDBP1))
- Alternative Name
- Ccndbp1 (CCNDBP1 Products)
- Synonyms
- CCNDBP1 Protein, dip1 Protein, gcip Protein, DIP1 Protein, GCIP Protein, HHM Protein, AU022347 Protein, Maid Protein, SECC-8 Protein, SSEC-8 Protein, cyclin D1 binding protein 1 Protein, cyclin D-type binding-protein 1 Protein, CCNDBP1 Protein, ccndbp1 Protein, Ccndbp1 Protein
- Background
- This gene was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Several alternatively spliced variants have been found for this gene.
- Molecular Weight
- 40.3 kDa
- NCBI Accession
- NP_036274
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