SERPINA9 Protein (AA 26-418) (His tag)

Catalog No. ABIN6387915

Product Details

Target: SERPINA9 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 9 (SERPINA9))

Protein Type: Recombinant

Protein Characteristics: AA 26-418

Origin: Mouse

Source: Baculovirus infected Insect Cells

Purification tag / Conjugate: This SERPINA9 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: NPYNQESSHL PSMKKNPASQ VSPSNTRFSF LLYQRLAQEN PGQNILFSPV SISTSLAMLS LGARSATKTQ ILRTLGFNFT WVSEPTIHMG FEYLVRSLNK CHQGRELRMG SVLFIRKELQ LQATFLDRVK KLYGAKVFSE DFSNAATAQA QINSYVEKET KGKVVDVIQD LDSQTAMVLV NHIFFKANWT QPFSTANTNK SFPFLLSKGT TVHVPMMHQT ESFAFGVDKE LGCSILQMDY RGDAVAFFVL PGKGKMRQLE KSLSARRLRK WSRSLQKRWI KVFIPKFSIS ASYNLETILP KMGIRDAFNS NADFSGITKT HFLQVSKAAH KAVLDVSEEG TEAAAATTTK LIVRSRDTPS SIIAFKEPFL ILLLDKNTES VLFLGKVENP RKMLEHHHHH H

Purity: > 85 % by SDS - PAGE

Endotoxin Level: < 1.0 EU per 1 microgram of protein (determined by LAL method)

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: SERPINA9 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 9 (SERPINA9))

Alternative Name: Serpina9 (SERPINA9 Products)

Synonyms: SERPINA9 Protein, 2310014L03Rik Protein, AW049635 Protein, Centerin Protein, GCET1 Protein, SERPINA11 Protein, SERPINA11b Protein, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9 Protein, serpin family A member 9 Protein, serpin A9 Protein, serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9 Protein, SPIA9 Protein, SERPINA9 Protein, LOC480423 Protein, Serpina9 Protein

Background: Serpina9, also known as serpin A9, is a member of the Serpin superfamily of serine protease inhibitors. Serpins are the most broadly distributed superfamily of protease inhibitors that use a conformational change to inhibit target enzymes. They are known to inhibit serine proteases and some are known to inhibit caspases and papain-like cysteine proteases. Serpins are conformational labile and many of the disease-linked mutations of serpins result in misfolding or in pathogenic, inactive polymers. This protein shows inhibition towards trypsin, thrombin, and plasmin and binds DNA and heparin. Recombinant mouse Serpina9, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Molecular Weight: 45.2kDa (401aa) 50-70KDa (SDS-PAGE under reducing conditions.)

NCBI Accession: NP_082273

UniProt: Q9D7D2