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PSCA Protein (AA 21-95) (His tag,AVI tag,Biotin)

PSCA Origin: Mouse Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
Catalog No. ABIN7013758
$1,675.38
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  • Target See all PSCA Proteins
    PSCA (Prostate Stem Cell Antigen (PSCA))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 21-95
    Origin
    • 10
    • 4
    Mouse
    Source
    • 5
    • 5
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This PSCA protein is labelled with His tag,AVI tag,Biotin.
    Purpose
    Biotinylated Mouse PSCA Protein, His,Avitag™ (MALS verified)
    Specificity
    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
    Purity
    >90 % as determined by SDS-PAGE.
    Endotoxin Level
    Less than 0.1 EU per μg by the LAL method.
  • Comment

    Ready-to-use Avitag™ biotinylated protein:
    The product is exclusively produced using the Avitag™ technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.

    This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Storage
    -20 °C
  • Target
    PSCA (Prostate Stem Cell Antigen (PSCA))
    Alternative Name
    PSCA (PSCA Products)
    Synonyms
    PRO232 Protein, 2210408B04Rik Protein, PSCA Protein, prostate stem cell antigen Protein, PSCA Protein, Psca Protein, LOC482068 Protein
    Background
    The Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol (GPI)-anchored protein, plays an important role in tumorigenesis. The prostate stem cell antigen (PSCA) gene, which encodes a prostate-specific antigen (PSA), was identified as a gene involved in cell adhesion and proliferation. PSCA may be involved in the regulation of cell proliferation. Has a cell-proliferation inhibition activity in vitro. May act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits nicotine-induced signaling probably implicating alpha-3:beta-2- or alpha-7-containing nAChRs.
    Molecular Weight
    12.0 kDa
    NCBI Accession
    NP_082492
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