DNTTIP2 Protein (AA 1-756) (His tag)
custom-made
DNTTIP2
Origin: Human
Host: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Target See all DNTTIP2 products
- DNTTIP2 (Deoxynucleotidyltransferase, Terminal, Interacting Protein 2 (DNTTIP2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-756
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This DNTTIP2 protein is labelled with His tag.
- Purpose
- Custom-made recombinant DNTTIP2 Protein expressed in mammalian cells.
- Sequence
- MVVTRSARAK ASIQAASAES SGQKSFAANG IQAHPESSTG SDARTTAESQ TTGKQSLIPR TPKARKRKSR TTGSLPKGTE PSTDGETSEA ESNYSVSEHH DTILRVTRRR QILIACSPVS SVRKKPKVTP TKESYTEEIV SEAESHVSGI SRIVLPTEKT TGARRSKAKS LTDPSQESHT EAISDAETSS SDISFSGIAT RRTRSMQRKL KAQTEKKDSK IVPGNEKQIV GTPVNSEDSD TRQTSHLQAR SLSEINKPNF YNNDFDDDFS HRSSENILTV HEQANVESLK ETKQNCKDLD EDANGITDEG KEINEKSSQL KNLSELQDTS LQQLVSQRHS TPQNKNAVSV HSNLNSEAVM KSLTQTFATV EVGRWNNNKK SPIKASDLTK FGDCGGSDDE EESTVISVSE DMNSEGNVDF ECDTKLYTSA PNTSQGKDNS VLLVLSSDES QQSENSENEE DTLCFVENSG QRESLSGDTG SLSCDNALFV IDTTPGMSAD KNFYLEEEDK ASEVAIEEEK EEEEDEKSEE DSSDHDENED EFSDEEDFLN STKAKLLKLT SSSIDPGLSI KQLGGLYINF NADKLQSNKR TLTQIKEKKK NELLQKAVIT PDFEKNHCVP PYSESKYQLQ KKRRKERQKT AGDGWFGMKA PEMTNELKND LKALKMRASM DPKRFYKKND RDGFPKYFQI GTIVDNPADF YHSRIPKKQR KRTIVEELLA DSEFRRYNRR KYSEIMAEKA ANAAGKKFRK KKKFRN Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
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Deoxynucleotidyltransferase, Terminal, Interacting Protein 2 (DNTTIP2) (AA 1-758) protein (His tag)
custom-made DNTTIP2 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- DNTTIP2 (Deoxynucleotidyltransferase, Terminal, Interacting Protein 2 (DNTTIP2))
- Alternative Name
- DNTTIP2 (DNTTIP2 Products)
- Background
- Deoxynucleotidyltransferase terminal-interacting protein 2 (Estrogen receptor-binding protein) (LPTS-interacting protein 2) (LPTS-RP2) (Terminal deoxynucleotidyltransferase-interacting factor 2) (TdIF2) (TdT-interacting factor 2),FUNCTION: Regulates the transcriptional activity of DNTT and ESR1. May function as a chromatin remodeling protein (PubMed:12786946, PubMed:15047147). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797). {ECO:0000269|PubMed:12786946, ECO:0000269|PubMed:15047147, ECO:0000269|PubMed:34516797}.
- Molecular Weight
- 84.5 kDa
- UniProt
- Q5QJE6
- AlphaFold
- Q5QJE6
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