TMEM198 Protein (AA 1-360) (His tag)
custom-made
TMEM198
Origin: Human
Host: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Target See all TMEM198 products
- TMEM198 (Transmembrane Protein 198 (TMEM198))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-360
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TMEM198 protein is labelled with His tag.
- Purpose
- Custom-made recombinant TMEM198 Protein expressed in mammalian cells.
- Sequence
- MPGTVATLRF QLLPPEPDDA FWGAPCEQPL ERRYQALPAL VCIMCCLFGV VYCFFGYRCF KAVLFLTGLL FGSVVIFLLC YRERVLETQL SAGASAGIAL GIGLLCGLVA MLVRSVGLFL VGLLLGLLLA AAALLGSAPY YQPGSVWGPL GLLLGGGLLC ALLTLRWPRP LTTLATAVTG AALIATAADY FAELLLLGRY VVERLRAAPV PPLCWRSWAL LALWPLLSLM GVLVQWRVTA EGDSHTEVVI SRQRRRVQLM RIRQQEDRKE KRRKKRPPRA PLRGPRAPPR PGPPDPAYRR RPVPIKRFNG DVLSPSYIQS FRDRQTGSSL SSFMASPTDA DYEYGSRGPL TACSGPPVRV Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
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Transmembrane Protein 198 (TMEM198) (AA 1-360) protein (His tag)
custom-made TMEM198 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- TMEM198 (Transmembrane Protein 198 (TMEM198))
- Alternative Name
- TMEM198 (TMEM198 Products)
- Background
- Transmembrane protein 198,FUNCTION: Promotes LRP6 phosphorylation by casein kinases and thereby plays a role in Wnt signaling. May be a membrane scaffold protein involved in the self-aggregation of LRP6 to further enhance its activity. {ECO:0000269|PubMed:21536646}.
- Molecular Weight
- 39.5 kDa
- UniProt
- Q66K66
- AlphaFold
- Q66K66
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