ASB4 Protein (AA 1-426) (His tag)
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- Target See all ASB4 Proteins
- ASB4 (Ankyrin Repeat and SOCS Box Containing 4 (ASB4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-426
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ASB4 protein is labelled with His tag.
- Purpose
- Custom-made recombinant Asb4 Protein expressed in mammalian cells.
- Sequence
- MDGITAPISK AGAAKLVKKD FLEALKTNDF GKLKAILIER QIDVDTVFEV EDENMILASY KQGYWLPSYK LKSSWATGLH LSVLLGHVEC LMVLLDHNAT INCRPNGKTP LHVACEIANL ECVKILCDRG AKLNCYSLSG HTALHFCTTP SSILCAKQLV LRGANVNMKT NNQDEETPLH TAAHFGLSEL VAFYVENGAI VDSMNAHMET PLAIATYWAL RFKEQEYSRE HHLICRTLLD NNAEVNARDD DFKSPLHKAA WNCDHVLMHM MLEAGAEANL MDINGCAAIQ YVLKVTSVRP AAQPEICYQL LLNHGAARIY PPQFHKVIQA CHSCPKAIEV VVNAYEHIRW NIKWRRAIPD DDLEKHWDFY HSLFKVCCNT PRTLMHLSRC AIRKALHNRC HKAIPMLSLP LPLKKYLLLE PEGIIY Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
- Top Product
- Discover our top product ASB4 Protein
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- ASB4 (Ankyrin Repeat and SOCS Box Containing 4 (ASB4))
- Alternative Name
- Asb4 (ASB4 Products)
- Background
- Ankyrin repeat and SOCS box protein 4 (ASB-4),FUNCTION: Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes differentiation and maturation of the vascular lineage by an oxygen-dependent mechanism. {ECO:0000269|PubMed:17636018}.
- Molecular Weight
- 48.1 kDa
- UniProt
- Q9WV71
- AlphaFold
- Q9WV71
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