GULP1 Protein (AA 1-304) (His tag)

Catalog No. ABIN7559496

Product Details

Target: GULP1 (GULP, Engulfment Adaptor PTB Domain Containing 1 (GULP1))

Protein Type: Recombinant

Protein Characteristics: AA 1-304

Origin: Mouse

Source: HEK-293 Cells

Purification tag / Conjugate: This GULP1 protein is labelled with His tag.

Purpose: Custom-made recombinant Gulp1 Protein expressed in mammalian cells.

Sequence: MNRAFSRKKD KTWMHTPEAL SKHYIPYNAK FLGSTEVEQP KGTEVVRDAV RKLKFARHIK KSEGQKIPKV ELQISIYGVK ILEPKTKEVQ HNCQLHRISF CADDKTDKRI FTFICKDSES NKHLCFVFDS EKCAEEITLT IGQAFDLAYR KFLESGGKDV ETRKQIAGMQ KRIQDLETEN MELKNKVQDL ESRLRTTQVS TSPAHGVTVM SPSTDIFDMI PFSPISHQSP TSARNGTQLP PIPSRSAETK RDLFGAEPFD PFNCGSGDFP PDIQSKLDEM QEGFKMGLTL EGTVFCLDPL DSRC Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Made to order protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a made-to-order protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: GULP1 (GULP, Engulfment Adaptor PTB Domain Containing 1 (GULP1))

Alternative Name: Gulp1 (GULP1 Products)

Background: PTB domain-containing engulfment adapter protein 1 (Cell death protein 6 homolog) (PTB domain adapter protein CED-6) (Protein GULP),FUNCTION: Modulates cellular glycosphingolipid and cholesterol transport. May play a role in the internalization of various LRP1 ligands, such as PSAP (By similarity). May function as an adapter protein. Required for efficient phagocytosis of apoptotic cells. Increases cellular levels of GTP-bound ARF6. {ECO:0000250, ECO:0000269|PubMed:17398097}.

Molecular Weight: 34.5 kDa

UniProt: Q8K2A1

AlphaFold: Q8K2A1