DMBX1 Protein (AA 1-381) (His tag)
custom-made
DMBX1
Origin: Mouse
Host: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Target See all DMBX1 Proteins
- DMBX1 (Diencephalon/mesencephalon Homeobox 1 (DMBX1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-381
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This DMBX1 protein is labelled with His tag.
- Purpose
- Custom-made recombinant Dmbx1 Protein expressed in mammalian cells.
- Sequence
- MQHYGVNGYS LHAMNSLSAM YNLHQQAAQQ AQHAPDYRPS VHALTLAERL AGCTFQDIIL EARYGSQHRK QRRSRTAFTA QQLEALEKTF QKTHYPDVVM RERLAMCTNL PEARVQVWFK NRRAKFRKKQ RSLQKEQLQK QKEAEGSHGE GKVEAPASDT QLETEQPPGL PSGDPPAELQ LSLSEQSASE SAPEDQLDRE EDSRAEEPKA EKSPGSESKV PGCKRGSPKA DSPGSLAITP AAPGGGLLGP SHSYSSSPLS LFRLQEQFRQ HMAATNNLMH YSSFEVGGPA PAAAAAAAAA VPYLGVNMAP LSSLHCQSYY QSLSAAAAAH QGVWGSPLLP APPTGLAPAS AALNSKTTSI ENLRLRAKQH AASLGLDTLP N Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
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Diencephalon/mesencephalon Homeobox 1 (DMBX1) (AA 1-382) protein (His tag)
custom-made DMBX1 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Diencephalon/mesencephalon Homeobox 1 (DMBX1) (AA 1-377) protein (GST tag)DMBX1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- DMBX1 (Diencephalon/mesencephalon Homeobox 1 (DMBX1))
- Alternative Name
- Dmbx1 (DMBX1 Products)
- Background
- Diencephalon/mesencephalon homeobox protein 1 (Diencephalon/mesencephalon-expressed brain homeobox gene 1 protein) (Orthodenticle homolog 3) (Paired-like homeobox protein DMBX1) (Paired-type homeobox Atx),FUNCTION: Functions as a transcriptional repressor. May repress OTX2-mediated transactivation by forming a heterodimer with OTX2 on the P3C (5'-TAATCCGATTA-3') sequence. Required for brain development, neonatal survival, postnatal growth, and nursing ability. {ECO:0000269|PubMed:11914943, ECO:0000269|PubMed:12055180, ECO:0000269|PubMed:15314164, ECO:0000269|PubMed:15890343}.
- Molecular Weight
- 41.1 kDa
- UniProt
- Q91ZK4
- AlphaFold
- Q91ZK4
- Pathways
- Feeding Behaviour
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