MICALL2 Protein (AA 1-1009) (His tag)
custom-made
MICALL2
Origin: Mouse
Host: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Target See all MICALL2 products
- MICALL2 (MICAL-Like 2 (MICALL2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-1009
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This MICALL2 protein is labelled with His tag.
- Purpose
- Custom-made recombinant Micall2 Protein expressed in mammalian cells.
- Sequence
- MAAIKALQEW CRQQCEGYRD VSITNMTTSF RDGLAFCAIL HRHRPDLINF SALRKENIYE NNKLAFQVAE EQLGIPALLD AEDMVALKVP DRLSILTYVS QYYNYFHGRS PIGGMAGIKR PSSDSTEELS GKKGLSQPAK LPSPAQTQRS PLSPARTNPV VQRNEGGSQR PSPKAAPGTA GSSVSSICGV CGKHVHLVQR HLADGRLYHR SCFRCKQCSS TLHSGAYRAT GEPGVFVCTH HSSEVTSVSP KSSNLASRKP GGVTADTRPF GVSWTVQEAN GEGTPLRVRT AAWEHAGGNT TAKGFVQTEL KPPSTSQVHV GSSAGPKLPT ITVTTTSVTS KALTHVTNSS PIGWSSPAQS SPANFNSRPV VSPSARNTHL PGSQGQTASK GVKTQLNLNS ESSNTAVTPA WTSSASKTQQ AREKFFQTPP SAPAPASAPA PAPTSKVPTV VTVPTSKVPN VVTAPTSKVP TVVTVPTSKV PTVVSAPTSK VPTVVSAPTS KVPTVVNSTN SRVTTVVNAP TSKVPTVVSA TNGRVPTVVT AHTGRVPAVM NTSASKVSPV VDAPAQESSR EQALSVLRKA LPALTGSGTQ APNRSFPATS SVLVTLPKNE VPQKVPSDKL SALTTQTPNF TIKLEPSAPV NVGNTAVFLQ AGKKSPSISP RVGKTSVGSR PQAEVAGVKG PGPISQEGQE EGPEGWRARL KPVDKKTPAG RSLEQKEPVL AEPRIGDTSR KASSSSDSSV HITLTSIQHK RKPCPAGSGP SPAALSPSPS HRKKLAVPPS LDVSADWLQP EPKKQEDGTR SCKEEKSPTR WSRERSAVLD SGLAPPGEAV TSPVRLHPDY IPQEELQRQL QDIESQLDAL ELRGVELEKR LRAAEGDASE DSLMVDWFRL IHEKQLLLRL ESELMYKSKD QRLEEQQLDL QGELRRLMDK PEGLKSPQDR QREQELLSQY VNTVNDRSDI VDFLDEDRLR EQEEDQMLEN MIQNLGLQRK KSKSFLSKIW SSKSKSGQA Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
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MICAL-Like 2 (MICALL2) (AA 1-904) protein (His tag)
custom-made MICALL2 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- MICALL2 (MICAL-Like 2 (MICALL2))
- Alternative Name
- Micall2 (MICALL2 Products)
- Background
- MICAL-like protein 2 (Junctional Rab13-binding protein) (Molecule interacting with CasL-like 2) (MICAL-L2),FUNCTION: Effector of small Rab GTPases which is involved in junctional complexes assembly through the regulation of cell adhesion molecules transport to the plasma membrane and actin cytoskeleton reorganization. Regulates the endocytic recycling of occludins, claudins and E-cadherin to the plasma membrane and may thereby regulate the establishment of tight junctions and adherens junctions. In parallel, may regulate actin cytoskeleton reorganization directly through interaction with F-actin or indirectly through actinins and filamins. Most probably involved in the processes of epithelial cell differentiation, cell spreading and neurite outgrowth. {ECO:0000269|PubMed:16525024, ECO:0000269|PubMed:18094055, ECO:0000269|PubMed:20008558, ECO:0000269|PubMed:23100251, ECO:0000269|PubMed:23890175}.
- Molecular Weight
- 108.3 kDa
- UniProt
- Q3TN34
- AlphaFold
- Q3TN34
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