ESCO1 Protein (AA 1-843) (His tag)

Catalog No. ABIN7564014

Product Details

Target: ESCO1 (Establishment of Cohesion 1 Homolog 1 (ESCO1))

Protein Type: Recombinant

Protein Characteristics: AA 1-843

Origin: Mouse

Source: HEK-293 Cells

Purification tag / Conjugate: This ESCO1 protein is labelled with His tag.

Purpose: Custom-made recombinant Esco1 Protein expressed in mammalian cells.

Sequence: MSIQEKSKEN SSIVTKESED ENLEEEVESS QNSPTKKSGS KEAVKTPVRF SNKSKTNESE FGMRMSTRSA SCSADKTATN SFNKNTVTLK GQSQESSKTK KLCQEKLSLG ILKGNEQLHR RSQRLQQLTE CTTRSLRSRE IHGQIQTVKQ NQQSARREQC NSTQSKCNKV KVNQKHVKRK VLEIKSDCKE DRHSVTNEVI NSPKGKKRKV QHQTTSTCSS QCNQGSEKCL QKTSRKEEIK PVPVTADIRK LKAATSVVSK KNELRKSAHT QVSTSTKRPQ IPLPLVPEHS DDQELEQAGK SKRGSILQLC EEIAGEIESD TVEVKKESSC VESVKEEKPA EVKLQGTDAE RQILHHKEAN QDVRSNRFFP SRKTKPVKCV LNGINSSTKK NSNWTKIKLS KFNSVQQHKL DSQVSPKLNL LQTGLSTSVL EMPHPVSQST FLEMKAHGNV TCQRDKMKGI KSEEVKINNI AIEINKATKR DPGNCNLDNH IKPSPDSSLD NQMKLSCESA PDQNFSICSA SEVETNPLEN TAAASTLLSQ AKIDEDRTFP GSAPNQQHSV LSDEASINRK NRDVPPNHSQ LKHDSHLEIT IPKSLKLKDS EKVDEKQLVI DAGHKRFGAV SCNICGMLYT ASNPEDETQH LLFHNQFISA VKYVGWKKER ILAEYPDGRI IMVLPEDPKY ALKKVDEIRE MVDNDLGFQQ APLMCYSRTK TLLFISNDKK VVGCLIAEHI QWGYRVIEEK LPVIRSEEEK VRFERQKAWC CSTLPEPAIC GISRIWVFSM MRRKKIASRM IECLRSNFIY GSYLSKEEIA FSDPTPDGKL FATQYCGTGQ FLVYNFINGQ NTT Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Made to order protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a made-to-order protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: ESCO1 (Establishment of Cohesion 1 Homolog 1 (ESCO1))

Alternative Name: Esco1 (ESCO1 Products)

Background: N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1),FUNCTION: Acetyltransferase required for the establishment of sister chromatid cohesion. Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during S phase. Acts by mediating the acetylation of cohesin component SMC3. {ECO:0000250|UniProtKB:Q5FWF5}.

Molecular Weight: 95.0 kDa

UniProt: Q69Z69

AlphaFold: Q69Z69