DEFB4A Protein

Catalog No. ABIN935228

Product Details

Target: DEFB4A (DEFB4) (Defensin, beta 4A (DEFB4))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Escherichia coli (E. coli)

Sequence: GIGDPVTCLK SGAICHPVFC PRRYKQIGTC GLPGTKCCKK P

Characteristics: Purified recombinant Human BD2 protein
Expression System: E.coli
Bioactivity: Determined by its ability to chemoattract immature human dendritic cells using a concentration of 10.0-100.0 ng/mL.

Purity: > 98 % pure

Endotoxin Level: < 0.1 ng per µg (1 EU/µg).

Application Details

Application Notes: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 10 mM Acetic Acid to a concentration of 0.1 - 1.0 mg/mL.

Buffer: Supplied lyophilized with no additives.

Preservative: Without preservative

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.

Target Details

Target: DEFB4A (DEFB4) (Defensin, beta 4A (DEFB4))

Alternative Name: BD2 (DEFB4 Products)

Background: Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The a-defensins are distinguished from the beta-defensins by the pairing of their three disulfide bonds. To date, four human beta-defensins have been identified, BD-1, BD-2, BD-3 and BD-4. beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they are chemoattractant towards immature dendritic cells and memory T cells.
Alternative Names: BD-2, BD 2 protein, BD-2 protein, SAP1 protein, BD2, Skin-antimicrobial peptide 1 protein, BD 2 protein, BD 2, BD-2 protein

Molecular Weight: 4.3 kDa