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Tmem123 may be used as a new maturation marker in DCs and that this molecule may be closely associated with the cell surface expression of CD40 (show CD40 Proteins).
This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death.
, keratinocytes associated transmembrane protein 3
, keratinocytes-associated transmembrane protein 3
, pro oncosis receptor inducing membrane injury
, pro-oncosis receptor inducing membrane injury
, serine/threonine-rich receptor
, transmembrane protein 123