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Human Polyclonal Recoverin Primary Antibody for ICC, IF - ABIN408191
Machali?ska, Kawa, Pius-Sadowska, Rogi?ska, K?os, Baumert, Wiszniewska, Machali?ski: Endogenous regeneration of damaged retinal pigment epithelium following low dose sodium iodate administration: an insight into the role of glial cells in retinal repair. in Experimental eye research 2013
Cow (Bovine) Polyclonal Recoverin Primary Antibody for WB - ABIN610629
Fuss, Wintergerst, Bartsch, Schachner: Molecular characterization and in situ mRNA localization of the neural recognition molecule J1-160/180: a modular structure similar to tenascin. in The Journal of cell biology 1993
High RCVRN expression is associated with renal tumors.
Crystal Structure of Recoverin with Calcium Ions Bound to Both Functional EF Hands.
Aberrant hypomethylation of the recoverin gene region, overlapping the promoter up-stream of the first exon and the first exon itself, is involved in the aberrant expression of recoverin in tumor cells.
recoverin has a pathological role in cancer-associated retinopathy
There are cis (show CISH Antibodies)-acting elements in the 5' non-coding region of the recoverin gene that are involved in the activation and suppression of gene expression.
Human recoverin is expressed in SCLC cells cultured from an anti-recoverin antibody-negative patient with CAR. KK0206 might be important for further research on SCLC related retinopathy.
A GRK1 (show GRK1 Antibodies) region close to its C-terminus also seemed to be the binding site for S-modulin/recoverin.
Rods and cones share the same isoforms of recoverin and GRK1 (show GRK1 Antibodies), and photoactivation also triggers a calcium decline in cones
recoverin may modulate the decay of light-activated PDE (show TWIST1 Antibodies)*, which may be responsible for the quickening of response recovery in background light.
High anti-recoverin antibody levels were achieved in two mouse models, accompanied by significantly reduced scotopic and photopic responses on the electroretinograms.
This is the first demonstration in an intact rod that light accelerates Rh* inactivation and that the Ca(2+)-binding protein (show PVALB Antibodies) recoverin may be required for the light-dependent modulation of Rh* lifetime.
recoverin undergoes light-dependent intracellular translocation in mouse rod photoreceptors
A novel rhodopsin-kinase (show GRK1 Antibodies)-binding site within the C-terminal region of recoverin.
(15) N NMR relaxation data suggest that Ca(2 (show CA2 Antibodies)+)-free recoverin undergoes millisecond conformational dynamics at particular amide sites throughout the protein.
Ca2 (show CA2 Antibodies)+-myristoyl switch in the neuronal calcium sensor requires different functions of Ca2 (show CA2 Antibodies)+-binding sites
Recoverin is a zinc-binding protein (show PTMS Antibodies)
Recoverin and rhodopsin kinase (show GRK1 Antibodies) have roles in a Ca2 (show CA2 Antibodies)+-dependent feedback loop in membrane rafts from rod outer segments
an interaction surface for the recoverin target rhodopsin kinase (show GRK1 Antibodies) is constituted upon Ca2 (show CA2 Antibodies)+ binding to the non-acylated mutant
Recoverin binds exclusively to an amphipathic peptide at the N terminus of rhodopsin kinase (show GRK1 Antibodies)
Ca2 (show CA2 Antibodies)+/recoverin has a role in regulating rhodopsin (show RHO Antibodies) mutants associated with retinitis pigmentosa
propose a novel role of the C-terminal segment of recoverin as an internal modulator of Ca(2 (show CA2 Antibodies)+) sensitivity
Time-resolved fluorescence shows biexponential fluorescence decay. The slower time constant was affected by Ca2 (show CA2 Antibodies)+-induced conformational changes in WT & RecE85Q (disabled EF-hand 2 (show HAND2 Antibodies)), & not RecE121Q (EF-hand 3 nonfunctional) with a clamped myristoyl group.
This gene encodes a member of the recoverin family of neuronal calcium sensors. The encoded protein contains three calcium-binding EF-hand domains and may prolong the termination of the phototransduction cascade in the retina by blocking the phosphorylation of photo-activated rhodopsin. Recoverin may be the antigen responsible for cancer-associated retinopathy.
cancer associated retinopathy antigen
, cancer-associated retinopathy protein
, 23 kDa photoreceptor cell-specific protein
, cancer associated retinopathy protein
, guanylate cyclase activator