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Key residues were identified to be responsible for the binding of arachidonic acid and anandamide with orphan human cytochrome P450 4X1.
PPARalpha (show PPARA Antibodies) has a role in CYP4X1 regulation, and the glucocorticoid and progesterone receptors have roles in CYP4Z1 (show CYP4Z1 Antibodies) gene activation
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The expression pattern of a similar rat protein suggests that this protein may be involved in neurovascular function in the brain.
cytochrome P450 4X1
, cytochrome P450, 4x1