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anti-Human RPSA Antibodies:
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Human Polyclonal RPSA Primary Antibody for IHC, IHC (p) - ABIN442947
Song, Choi, Cho, Sung, Song, Kim, Bae, Lee, Kim: Expression of 67-kDa laminin receptor was associated with tumor progression and poor prognosis in epithelial ovarian cancer. in Gynecologic oncology 2012
Show all 2 Pubmed References
Chicken Polyclonal RPSA Primary Antibody for WB - ABIN610969
Saitoh, Pizzi, Wang: Perturbation of SUMOlation enzyme Ubc9 by distinct domain within nucleoporin RanBP2/Nup358. in The Journal of biological chemistry 2002
Show all 2 Pubmed References
Human Monoclonal RPSA Primary Antibody for IF (p), IHC (p) - ABIN1713335
Wang, Yu, Guan, Liu, Qiao: 67-kDa Laminin receptor contributes to hypoxia-induced migration and invasion of trophoblast-like cells by mediating matrix metalloproteinase-9. in Clinical and experimental pharmacology & physiology 2015
The binding of laminin-1 (show LAMA1 Antibodies) to 67LR causes initial signaling through PKA and Epac (show RAPGEF3 Antibodies), which causes the internalization of 67LR, along with signaling enzymes, such as adenylyl cyclase, into early endosomes. This causes sustained signaling for protection against neuronal cell death induced by serum withdrawal.
We suggest that PrP(C (show PRNP Antibodies)) and its interactor, LR/37/67 kDa, could be potential therapeutic targets for schwannomas and other Merlin (show NF2 Antibodies)-deficient tumours.
Our results suggest that hypoxia-elicited c-Jun/activator protein 1 (show JUN Antibodies) regulates 37-kDa laminin receptor precursor expression, which modulates migration and invasion of lung adenocarcinoma cells
Increased LRP levels correlate with the increased invasive and adhesive potential in early and late stage melanoma cells.
A polysaccharide from Pinellia ternata inhibits cell proliferation and metastasis in human cholangiocarcinoma cells by targeting of Cdc42 (show CDC42 Antibodies) and 67kDa Laminin Receptor
67LR plays a considerable role in the development of colon cancer multidrug resistance
37LRP regulates the metastasis of glioma cells in vitro and tumor growth in vivo.
Higher molecular weight Rpsa requires sumoylation to form.
Knock-Down of the 37kDa (show LRRC17 Antibodies)/67kDa Laminin Receptor LRP/LR Impedes Telomerase Activity
Report discovery of new small molecules inhibiting 67 kDa laminin receptor interaction with laminin and cancer cell invasivness.
High 67-kDa laminin receptor expression is associated with obesity-induced inflammation.
Results indicate that MGr1-Ag/37LRP contributes to laminin-mediated cell adhesion-mediated drug resistance in gastric cancer cells.
a high plasticity of RPSA, which could be important for its multiple cellular localizations and functional interactions
Laminin receptor activation inhibits endothelial TF expression by impairing JNK (show MAPK8 Antibodies) phosphorylation
protective role of TGF-beta1 (show TGFB1 Antibodies)-dependent up-regulation of the 37/67 LR in cardiomyocytes in cardiac remodelling with increased laminin expression
Reduced expression of the TLR4 (show TLR4 Antibodies) signaling pathway involves both the 67-kDa laminin receptor and Toll-interacting protein Tollip (show TOLLIP Antibodies), leading to consequent inflammatory responses.
laminin receptor precursor protein interacts with doppel (show PRND Antibodies)
An N-terminally truncated laminin receptor mutant encompassing the extracellular domain reduces the binding of recombinant cellular huPrP to mouse neuroblastoma (show ARHGEF16 Antibodies) cells,and interferes with the PrP(Sc) propagation.
LamR plays a role in transduction by three other closely related serotypes (adeno (show ADORA2A Antibodies)-associated virus serotype 2 (AAV2), -3, and -9)
both eEF1A (show EEF1A2 Antibodies) and MYPT1 (show PPP1R12A Antibodies) have roles in EGCG signaling for cancer prevention through 67LR
These results indicate that LamR is a cellular attachment receptor for classical Swine Fever virus.
Dengue virus serotypes 1, 2 and 3 all interact with the 37 kDa/67 kDa laminin receptor (LAMR1), a common non-integrin surface protein on many cell types.
isolated a ribosomal protein SA cDNA that consists of 1064 bp with an open reading frame of 885 bp encoding a 295 aa protein
Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of this gene exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
37 kDa laminin receptor
, 37/67 kDa laminin receptor
, 67 kDa laminin receptor
, Laminin receptor 1
, Laminin-binding protein precursor p40
, ribosomal protein SA
, 40S ribosomal protein SA
, laminin-binding protein precursor p40
, colon carcinoma laminin-binding protein
, laminin receptor 1 (67kD, ribosomal protein SA)
, multidrug resistance-associated protein MGr1-Ag
, 37 kDa oncofetal antigen
, P40-3, functional
, P40-8, functional
, laminin receptor 1 (ribosomal protein SA)
, 37kD Laminin receptor
, laminin receptor 1
, laminin receptor 1 (ribosomal protein SA, 67 kDA)
, ribosomal protein SA pseudogene
, laminin receptor