Browse our SRSF10 Proteins (SRSF10)

Full name:: serine/arginine-Rich Splicing Factor 10 Proteins (SRSF10)

On www.antibodies-online.com are 4 serine/arginine-Rich Splicing Factor 10 (SRSF10) Proteins from 3 different suppliers available. Additionally we are shipping SRSF10 Antibodies (67) and many more products for this protein. A total of 79 SRSF10 products are currently listed.

Synonyms:: fusip1, fusip2, nssr, NSSR1, NSSR2, sfrs13, sfrs13a, srp38, srrp40, Srsf13a, tasr, tasr1, tasr2

list all proteins	Gene Name	GeneID	UniProt
	SRSF10	10772	O75494
	SRSF10	14105	Q9R0U0
Rat SRSF10	SRSF10	362630
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Human serine/arginine-Rich Splicing Factor 10 (SRSF10) interaction partners

DNA damage co-opts SRSF10 to control splicing decisions in transcripts encoding components involved in DNA repair, cell-cycle control, and apoptosis.
Results show that YTHDC1 (show YTHDC1 Proteins) promotes exon inclusion in targeted mRNAs through recruiting pre-mRNA splicing factor (show SNRPB Proteins) SRSF3 (show SRSF3 Proteins) while blocking SRSF10 mRNA binding.
SRSF10 is a key regulator of BCLAF1 pre-mRNA splicing and the maintenance of oncogenic features in human colon cancer cells
In colorectal cancer, NSSR1 was highly expressed in the nucleus of tumor cells.
Splicing thermotolerance is acquired through maintenance of SRSF10 phosphorylation and that this is mediated at least in part by Hsp27 (show HSPB1 Proteins).
Data show that SFRS13A expression was significantly associated with LDLR (show LDLR Proteins) splicing efficiency in vivo.
found to be dephosphorylated specifically in mitotic cells; show that dephosphorylated SRp38 is required for the observed splicing repression
SRp38 plays a crucial role in cell survival under stress conditions by inhibiting the splicing machinery
SRp38 contains two arginine- and serine-rich domains (RS), one of which has a unique, second-step repression activity, while both function together as a splicing repression domain.

Mouse (Murine) serine/arginine-Rich Splicing Factor 10 (SRSF10) interaction partners

SRSF10 represses inclusion of PGC1alpha exon 7a.
The results of this study suggested for the first time that NSSR1 may provide a novel mechanism for reducing neuronal injury after ischemia, probably through regulation on alternative splicing of NCAM-L1 (show L1CAM Proteins) and CREB (show CREB1 Proteins) in astrocytes.
We further show that an SRSRSK sequence in the RS3 (show EDAR Proteins) domain may play an important role in the function of NSSR1 in pre-mRNA splicing.
These results identify SRSF10 as an essential regulator for adipocyte differentiation.
the potential roles of NSSR1 in sperm maturation and fertilization
NSSR1 mRNA was expressed in mouse cerebrum, cerebellum, heart, liver, intestine, kidney and lung tissue, but NSSR1 protein was only expressed in neural tissues.
found to be dephosphorylated specifically in mitotic cells; show that dephosphorylated SRp38 is required for the observed splicing repression
The NSSR1 promotes neuronal differentiation and the splicing of NCAML1 (show L1CAM Proteins) exon2 and TrkC (show NTRK3 Proteins)-K1.
NSSR1 and NSSR2 function as splicing modulators via binding to pre-mRNAs.
The findings for the first time provide the evidence indicating the potential importance of NSSR1 in testes development, spermatogenesis and cryptorchidism.

SRSF10 Protein Profile

Protein Summary

This gene product is a member of the serine-arginine (SR) family of proteins, which is involved in constitutive and regulated RNA splicing. Members of this family are characterized by N-terminal RNP1 and RNP2 motifs, which are required for binding to RNA, and multiple C-terminal SR/RS repeats, which are important in mediating association with other cellular proteins. This protein can influence splice site selection of adenovirus E1A pre-mRNA. It interacts with the oncoprotein TLS, and abrogates the influence of TLS on E1A pre-mRNA splicing. This gene has multiple pseudogenes. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. In addition, transcript variants utilizing alternative polyA sites exist.

Alternative names and synonyms associated with SRSF10

serine and arginine rich splicing factor 10 (SRSF10)
serine/arginine-rich splicing factor 10 (SRSF10)
serine/arginine-rich splicing factor 10 (Srsf10)
serine/arginine-rich splicing factor 10 S homeolog (srsf10.S)
serine and arginine rich splicing factor 10 (Srsf10)

fusip1 protein
fusip2 protein
nssr protein
NSSR1 protein
NSSR2 protein
sfrs13 protein
sfrs13a protein
srp38 protein
srrp40 protein
Srsf13a protein
tasr protein
tasr1 protein
tasr2 protein

Protein level used designations for SRSF10

, , , , , , , , , , , , , , , , , , , , , , serine/arginine-rich splicing factor 10 FUS interacting protein (serine-arginine rich) 1 FUS interacting protein (serine/arginine-rich) 1 splicing factor, arginine/serine-rich 13A 40 kDa SR-repressor protein FUS-interacting protein (serine-arginine rich) 2 FUS-interacting serine-arginine-rich protein 1 SR splicing factor 10 TLS-associated SR protein TLS-associated protein TASR TLS-associated protein with SR repeats TLS-associated protein with Ser-Arg repeats TLS-associated serine-arginine protein 1 TLS-associated serine-arginine protein 2 neural-salient SR protein serine-arginine repressor protein (40 kDa) splicing factor SRp38 splicing factor, arginine/serine-rich 13 Fus-associated protein with serine-arginine repeats TLS-associated serine-arginine protein neural-salient serine/arginine-rich protein neural-specific SR protein serine/arginine-rich splicing factor 13A

GENE ID	SPECIES
610494	Canis lupus familiaris
100071526	Equus caballus
100478134	Ailuropoda melanoleuca
419689	Gallus gallus
10772	Homo sapiens
14105	Mus musculus
379343	Xenopus laevis
362630	Rattus norvegicus
768310	Bos taurus

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