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We hope this work will be useful to understand the general characteristics of DHFRL1.
The DHFRP4, or dihydrofolate reductase-like 1 (DHFRL1), gene is expressed and shares some commonalities with DHFR (show DHFR Proteins).
Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Binds its own mRNA and that of DHFR.
dihydrofolate reductase pseudogene 4
, dihydrofolate reductase, mitochondrial
, dihydrofolate reductase-like protein 1
, dihydrofolate reductase-like 1