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Browse our anti-Uridine Monophosphate Synthetase (UMPS) Antibodies

Full name:: anti-Uridine Monophosphate Synthetase Antibodies (UMPS)

On www.antibodies-online.com are 65 Uridine Monophosphate Synthetase (UMPS) Antibodies from 16 different suppliers available. Additionally we are shipping Uridine Monophosphate Synthetase Proteins (11) and and many more products for this protein. A total of 82 Uridine Monophosphate Synthetase products are currently listed.

Synonyms:: 1700095D23Rik, AA408257, AL033308, BB164745, OPRT, UMPS, zgc:55702, zgc:55723

list all antibodies	Gene Name	GeneID	UniProt
	UMPS	7372	P11172
	UMPS	22247	P13439
	UMPS	288051
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Most Popular Reactivities for anti-Uridine Monophosphate Synthetase (UMPS) Antibodies

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Relevant Pathways for anti-Uridine Monophosphate Synthetase Antibodies

Ribonucleoside Biosynthetic Process

More product categories related to Uridine Monophosphate Synthetase Antibody

Top referenced anti-Uridine Monophosphate Synthetase Antibodies

Cow (Bovine) Polyclonal UMPS Primary Antibody for IHC, WB - ABIN2783243 : Ishikawa, Kondo, Yamaguchi, Sakamoto, Fujisawa: Effect of varicocelectomy on patients with unobstructive azoospermia and severe oligospermia. in BJU international 2008 (PubMed)
Show all 2 Pubmed References
Human Monoclonal UMPS Primary Antibody for IF, ELISA - ABIN521260 : Griffith, Mwenifumbo, Cheung, Paul, Pugh, Tang, Chittaranjan, Morin, Asano, Ally, Miao, Lee, Chan, Taylor, Severson, Hou, Griffith, Cheng, Novik, Moore, Luk, Owen, Brown, Morin, Gill, Tai, Marra: Novel mRNA isoforms and mutations of uridine monophosphate synthetase and 5-fluorouracil resistance in colorectal cancer. in The pharmacogenomics journal 2013 (PubMed)
Human Monoclonal UMPS Primary Antibody for IF, ELISA - ABIN521259 : Koopman, Venderbosch, van Tinteren, Ligtenberg, Nagtegaal, Van Krieken, Punt: Predictive and prognostic markers for the outcome of chemotherapy in advanced colorectal cancer, a retrospective analysis of the phase III randomised CAIRO study. in European journal of cancer (Oxford, England : 1990) 2009 (PubMed)

More Antibodies against Uridine Monophosphate Synthetase Interaction Partners

Caenorhabditis elegans (C. elegans) Uridine Monophosphate Synthetase (UMPS) interaction partners

the conserved uridine monophosphate phosphoribosyltransferase (UMPS), which acts in pyrimidine biosynthesis, is required for NAD(+) biosynthesis in place of the missing QPRTase

Human Uridine Monophosphate Synthetase (UMPS) interaction partners

Partial UMPS-deficiency should be included in the differential diagnosis of mild orotic aciduria.
The UMPS 638 CC genotype might be a candidate biomarker predicting toxicity in patients receiving tegafur-uracil/leucovorin-based preoperative chemoradiation for locally advanced rectal cancer
OPRT transition state analogues identify crucial components of potent inhibitors targeting OPRT enzymes.
The observed mutations, aberrant splicing and downregulation of UMPS represent novel mechanisms for acquired 5-FU resistance in colorectal cancer
[review] It is confirmed that the type I defect in hereditary orotic aciduria is caused by loss of uridine monophosphate (UMP)synthase activity
OPRT expression in colorectal carcinoma tissues is not correlated with the toxicity of 5-FU, but OPRT expression in the normal tissues can help predict the toxicity associated with 5-FU.
High expression levels of orotate phosphoribosyl transferase and thymidylate synthase in colorectal cancer appear to be significantly involved in metastasis after curative surgery
Although no association was detected between UMPS variants and gastrointestinal cancer risk in Caucasians, polymerase chain reaction-RFLP with BsrI digestion and DHPLC set up at 59 degrees C are reliable and cost-effective methods to genotype UMPS.
novel phosphoribosyltransferase transition states
orotate phosphoribosyl transferase/DPD ratio has a relation to cancer staging and survival rate.
Increased orotate phosphoribosyltransferase expression is associated with bladder cancers.
expression of OPRT gene and the OPRT/dihydropyrimidine dehydrogenase ratio might be useful as predictive parameters for the efficacy of fluoropyrimidine-based chemotherapy for metastatic colorectal cancer
thymidylate synthase and orotate phosphoribosyl transferase, but not dihydropyrimidine dehydrogenase, are more highly expressed in prostate cancer than in benign prostatic hyperplasia
orotate phosphoribosyl transferase has a role in lymph node metastasis of gastric cancer
The investigated SNPs of OPRT may have no major influence on 5-FU sensitivity.
The OPRT Gly213Ala polymorphism seems to be a useful marker for predicting toxicity to bolus 5-FU chemotherapy.
Overexpression of the OPRT gene plays an important role in the antiproliferative effect of 5-FU.
High expression of OPRT is associated with the response to adjuvant chemotherapy in human pancreatic cancer
data suggest that OPRT is involved in early events of pancreatic and gallbladder carcinogenesis and invasion of hepatocellular carcinomas
decreased the sensitivities of the cultured tumor cells to 5-FU. These results suggest that the OPRT expression level in tumors is an additional determinant of the efficacy of 5-FU.

Uridine Monophosphate Synthetase (UMPS) Antigen Profile

Antigen Summary

This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.

Alternative names and synonyms associated with Uridine Monophosphate Synthetase (UMPS)

Orotidine 5'-phosphate decarboxylase (umps-1) antibody
uridine monophosphate synthetase (umps) antibody
uridine monophosphate synthetase L homeolog (umps.L) antibody
uridine monophosphate synthetase (UMPS) antibody
uridine 5'-monophosphate synthase (LOC100556619) antibody
uridine monophosphate synthetase (Umps) antibody

1700095D23Rik antibody
AA408257 antibody
AL033308 antibody
BB164745 antibody
OPRT antibody
UMPS antibody
zgc:55702 antibody
zgc:55723 antibody

Protein level used designations for UMPS

Uridine MonoPhosphate Synthetase family member (umps-1) , uridine 5'-monophosphate synthase , uridine monophosphate synthetase , uridine monophosphate synthase , uridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5'-decarboxylase) , OMPdecase , OPRTase , UMP synthase , orotate phosphoribosyltransferase , orotidine 5'-phosphate decarboxylase , orotate phosphoribosyl transferase and orotidine-5'-decarboxylase

GENE ID	SPECIES
176453	Caenorhabditis elegans
393143	Danio rerio
494728	Xenopus laevis
100070386	Equus caballus
100353794	Oryctolagus cuniculus
100556619	Anolis carolinensis
424256	Gallus gallus
460644	Pan troglodytes
496817	Xenopus (Silurana) tropicalis
715664	Macaca mulatta
780512	Ovis aries
7372	Homo sapiens
478593	Canis lupus familiaris
281568	Bos taurus
22247	Mus musculus
288051	Rattus norvegicus

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Show all anti-Uridine Monophosphate Synthetase (UMPS) Antibodies with Pubmed References

Caenorhabditis elegans (C. elegans) Uridine Monophosphate Synthetase (UMPS) interaction partners

Human Uridine Monophosphate Synthetase (UMPS) interaction partners

Antigen Summary

Alternative names and synonyms associated with Uridine Monophosphate Synthetase (UMPS)

Protein level used designations for UMPS