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anti-Mouse (Murine) Ephrin A1 Antibodies:
anti-Rat (Rattus) Ephrin A1 Antibodies:
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Mouse (Murine) Polyclonal Ephrin A1 Primary Antibody for ELISA, WB - ABIN4308733
Zhang, Zeng, Briggs, Beaty, Simons, Chiu Yen, Tyler, Tsai, Ye, Gesell, Herman, Baylin, Watkins: A potential tumor suppressor role for Hic1 in breast cancer through transcriptional repression of ephrin-A1. in Oncogene 2010
In myelinating co-cultures and in zebrafish, we find that the number of mature oligodendrocytes does not change as result of manipulating signaling through the ephrinA1-EphA4 (show EPHA3 Antibodies) system. However, in both systems, inhibition of EphA4 (show EPHA3 Antibodies) signaling leads to a higher number of myelin sheaths formed by each oligodendrocyte. In isolated oligodendrocyte cultures, activation of EphA4 (show EPHA3 Antibodies) reduced process extension.
EphA2 (show EPHA2 Antibodies) mAb treatment could partially inhibit LPSinduced inactivation of EphBEphrin B3 signalling, while Ephrin B3 (show EFNB3 Antibodies) overexpression could abrogate LPSinduced activation of EphA2Ephrin A1 signalling. EphB1 (show EPHB1 Antibodies)/Ephrin B3 (show EFNB3 Antibodies) signalling may antagonise the EphA2 (show EPHA2 Antibodies)/Ephrin A1dependent pathway following LPS (show TLR4 Antibodies) treatment.
Collectively, these data suggest that ATRA attenuates bleomycin-induced pulmonary fibrosis by regulating EphA2 (show EPHA2 Antibodies)-EphrinA1 and PI3K-Akt (show AKT1 Antibodies) signaling.
Lipopolysaccharide exposure significantly up-regulated EphA2 (show EPHA2 Antibodies) and EphrinA1 expression.
Activation of EphA1 (show EPHA1 Antibodies)-Epha receptor axis attenuates diabetic nephropathy in mice.
Following ephrin-A1 stimulation, truncated EphA2 (show EPHA2 Antibodies) did not detectably interfere with the phosphorylation of endogenous EphA2 (show EPHA2 Antibodies), and it potentiated cell adhesion possibly through modulation of integrin avidity.
ADAM12 (show ADAM12 Antibodies) enhanced ephrin-A1 cleavage in response to transforming growth factor-betra1 in primary tumors.
S100A8 (show S100A8 Antibodies) and ephrin-A1 contribute to lung metastasis.
We used in utero electroporation-mediated EphA7 overexpression in developing somatosensory corticothalamic axons to dissect EphA7/ephrin-A-dependent mechanisms involved in regulating both initial targeting and postnatal growth of the CT projections.
Elevated levels of ephrin-A1 may contribute to diabetic keratopathies by persistently engaging EphA2 (show EPHA2 Antibodies) and prohibiting Akt (show AKT1 Antibodies)-dependent corneal epithelial repair processes.
Data indicate that ephrin-A1 regulates cardiac valve development, making ephrin-A1-deficient mice a novel model for congenital heart defects.
ephrin-A1 seems to be remarkably involved in elementary processes of endothelial migration like cellular polarization, migratory direction and speed.
Findings show that EFNA1 expression is a useful marker for predicting a high risk of recurrence in hepatocellular carcinoma patients but not EPHA2 (show EPHA2 Antibodies).
Results suggest that EFNA1 is involved in colorectal tumorigenesis, and rs12904 A>G polymorphism in the 3' UTR (show UTS2R Antibodies) of EFNA1 is associated with CRC (show CALR Antibodies) susceptibility in a Chinese population.
EphA2 (show EPHA2 Antibodies)-ephrinA1 trans-endocytosis is sensitive to the mechanical properties of a cell's microenvironment
Ephrin-A1 is upregulated in tumor microenvironment and promotes angiogenesis through a coordinated cross-talk with PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies)-dependent eNOS (show NOS3 Antibodies) activation.
The interaction between ephrin-As, Eph (show EPHA1 Antibodies) receptors and integrin alpha3 is plausibly important for the crosstalk between Eph (show EPHA1 Antibodies) and integrin signalling pathways at the membrane protrusions and in the migration of brain cancer cells.
Increased expression of EFNA1 mRNA is associated with gastric cancer.
Expression of EPHRIN-A1 tends to be associated with worse survival in head and neck cancer.
EFNA1 expression is a useful marker for predicting high risk of relapse and cancer-related death in patients who have undergone curative resection for CRC (show CALR Antibodies).
Findings suggest that the glycosylation on ephrin-A1 plays a critical role in the binding and activation of the EphA2 (show EPHA2 Antibodies) receptor.
expression of Eph (show EPHA1 Antibodies) A1, A2, A4, and A7 was strongly detected in endometrial epithelial cells during early pregnancy.
The Eph-Ephrin A system might play an important role in regulating the swine contact between blastocysts and endometrium during embryo implantation.
Eph (show EPHA1 Antibodies) A-ephrin A1 system is a positive factor in the increase and maintenance of epithelial cells in mammary glands of cows; the signaling system contributes to development, remodeling, and functionality of normal mammary glands and could overcome mastitis.
This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin which binds to the EPHA2, EPHA4, EPHA5, EPHA6, and EPHA7 receptors. Two transcript variants that encode different isoforms were identified through sequence analysis.
EPH-related receptor tyrosine kinase ligand 1
, eph ligand family-a
, ephrin A1
, immediate early response protein B61
, TNF alpha-induced protein 4
, eph-related receptor tyrosine kinase ligand 1
, ligand of eph-related kinase 1
, tumor necrosis factor alpha-induced protein 4
, tumor necrosis factor, alpha-induced protein 4
, ephrin-A1 b